WormBase Tree Display for Variation: WBVar00249471

WBVar00249471 Name: Public_name: tm423
    Other_name: CE07800:p.Thr330_Gln419delextTer?
      C01G5.8a.1:c.988_1257del
      C01G5.8b.1:c.-285_-16del
    HGVSg: CHROMOSOME_IV:g.6550140_6550550del
  Sequence_details: SMap: S_parent: Sequence: C01G5
    Flanking_sequences: atctcagatgtcgttgccttgaagaatgtg gatttattgttagtcataaatctcttgtac
    Mapping_target: C01G5
    Source_location: 7 CHROMOSOME_IV 6550139 6550551 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm423_external
      tm423_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00005206
      WBStrain00034667
      WBStrain00040548
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 423
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00015310
    Transcript: C01G5.8a.1 (11)
      C01G5.8b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C01G5.8b.1:c.-285_-16del
        cDNA_position: 1000-1269
        Intron_number: 7-8/16
        Exon_number: 7-9/17
  Isolation: Mutagen: TMP/UV
  Genetics: Map: IV
  Description: Phenotype: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0001781 Paper_evidence: WBPaper00036759
        Curator_confirmed: WBPerson3875
        Remark: hypersensitive to cisplatin treatment Paper_evidence: WBPaper00036759
            Curator_confirmed: WBPerson3875
        Rescued_by_transgene: WBTransgene00007773
        Affected_by: Molecule: WBMol:00002867 Paper_evidence: WBPaper00036759
              Curator_confirmed: WBPerson3875
    Phenotype_not_observed: WBPhenotype:0000054 Paper_evidence: WBPaper00036759
        Curator_confirmed: WBPerson3875
  Disease_info: Models_disease: DOID:13636
    Models_disease_in_annotation: WBDOannot00000858
  Reference: WBPaper00036759
  Remark: 36309/36310-36720/36721 (411 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele