WormBase Tree Display for Variation: WBVar00249789

WBVar00249789 Name: Public_name: tm760
    Other_name: C08A9.1.1:c.53+143_364-76del
    HGVSg: CHROMOSOME_X:g.17092963_17093677del
  Sequence_details: SMap: S_parent: Sequence: C08A9
    Flanking_sequences: ataattaatttttgcaagctccttttaaat gatgtttctttattaacattttcgttaata
    Mapping_target: C08A9
    Source_location: 7 CHROMOSOME_X 17092962 17093678 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm760_external
      tm760_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00007661
      WBStrain00026684
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 760
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00015583
      WBGene00004932
    Transcript: C08A9.1.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C08A9.1.1:c.53+143_364-76del
        Intron_number: 2-4/6
        Exon_number: 3-4/7
      C08A9.3a.1 VEP_consequence: splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        Intron_number: 2/16
        Exon_number: 1-2/17
    Interactor (18)
  Isolation: Mutagen: TMP/UV
  Genetics: Map: X
  Description: Phenotype_not_observed: WBPhenotype:0000039 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. S. Yanase: normal lifespan on 20C Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Comment to the NBP from Dr. S. Yanase: normal lifespan on 20C. Dr. S. Hekimi: PLoS Genetics 5, e1000361 (2009). Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000308 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. G. Ruvkun to the National Bioresource Project of Japan: no effect on dauer arrest. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000520 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. WB Derry to the National Bioresource Project of Japan: WT morphology. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0001739 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. M. Driscoll: no significant effects on aging. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
  Reference: WBPaper00065316
  Remark: 14553/14554-15268/15269 (715 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele