WormBase Tree Display for Variation: WBVar00249822

WBVar00249822 Name: Public_name: tm794
    Other_name: C16C10.7b.1:c.69-5_316-163del
      C16C10.7a.1:c.69-5_316-163del
    HGVSg: CHROMOSOME_III:g.4165523_4166169del
  Sequence_details: SMap: S_parent: Sequence: C16C10
    Flanking_sequences: tgcaaaaagcaaacattttgtcagctttct aaattacgattattaaattttggaaattct
    Mapping_target: C16C10
    Source_location: 7 CHROMOSOME_III 4165522 4166170 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm794_external
      tm794_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00007570
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 794
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00004381
    Transcript: C16C10.7a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C16C10.7a.1:c.69-5_316-163del
        Intron_number: 2-3/5
        Exon_number: 3/6
      C16C10.7b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C16C10.7b.1:c.69-5_316-163del
        Intron_number: 2-3/6
        Exon_number: 3/7
    Interactor: WBInteraction000501984
      WBInteraction000519125
      WBInteraction000519470
      WBInteraction000541898
      WBInteraction000541899
      WBInteraction000541900
      WBInteraction000541901
      WBInteraction000541902
  Isolation: Mutagen: TMP/UV
  Genetics: Map: III
  Description: Phenotype: WBPhenotype:0000195 Paper_evidence: WBPaper00040713
        Curator_confirmed: WBPerson712
        Remark: Animals have low penetrance, but reproducible defects in the migration of the posterior DTC. Paper_evidence: WBPaper00040713
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00040713
          Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000062 Paper_evidence: WBPaper00040713
        Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Comment to the NBP from: Dr. Z. Ronai: J. Cell Biol. 165, 857-867 (2004). Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
          Animals are viable. Paper_evidence: WBPaper00040713
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00040713
          Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Paper_evidence: WBPaper00040713
        Curator_confirmed: WBPerson712
        Remark: Animals are fertile. Paper_evidence: WBPaper00040713
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00040713
          Curator_confirmed: WBPerson712
  Reference: WBPaper00040713
  Remark: 22868/22869-23515/23516 (647 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele