WormBase Tree Display for Variation: WBVar00249961

WBVar00249961 Name: Public_name: tm939
    Other_name: CE09016:p.Thr85LeufsTer15
      C55B7.5.1:c.253_898del
    HGVSg: CHROMOSOME_I:g.6494749_6495394del
  Sequence_details: SMap: S_parent: Sequence: C55B7
    Flanking_sequences: gcaaactattacggagaatgcagcattcat ctgatgataatatcgagaaaagcaataatt
    Mapping_target: C55B7
    Source_location: 7 CHROMOSOME_I 6494748 6495395 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm939_external
      tm939_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 939
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00016944
      WBGene00007018
    Transcript: C55B7.9a.3 VEP_consequence: 5_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: ?-6
        Exon_number: 1/10
      C55B7.5.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: C55B7.5.1:c.253_898del
        HGVSp: CE09016:p.Thr85LeufsTer15
        cDNA_position: 292-937
        CDS_position: 253-898
        Protein_position: 85-300
        Exon_number: 4/6
        Codon_change: ACAGCTGAAAAGATCTTGGATCGGAGAGTTTCTGAAATGAGAAGGCAGCGTGAGGAAGGTCTCGATTCAATTCGAATGTTGGATGACAAAATAAAGTTTGCTCAAGATAATTTCTCATCTGTTTCGATTGATGGAGGACCTATCGAAATTGTCGAGAAATACGATGAAGAGATGGAAAAACTGTTTTATCAAAATCGCAAAAACAAAAAGATGTCTCAAAATGATGAACAGAACGAGAAGATAATAGAAAAGAACAAATTGAATGGTGACCAAGATCACAACGATGTGATGAACCGTTTGGAAGAACTAGAGAAACTGGAACAAGACAATGATGAGATGGAAGAAGCTCCAATTCCGAAACCTTTTGAAGTTTCAAACGAAGATTTACAGGATTTGGGTAAATTAGAGGAAGTTGAGGAAGTTGAACAAGATCCAACTGATAAAAAACTAAGATTTGGAATGAATGAACGTTTGCTGGCACAACCTGGAGTAACACAGAAGGAAATGGAACGGCTGTTAGATTTCTTAGACACTTGTGATGAAGAGAGTTCCGATGAGGAGTATGATGAAGATGAAGAGGAAGGAGACGATGATGAAGAGAATCTTAACAATAGTGTAGAAGAACTCGACTCTGATGATTATGCATct/ct
        Amino_acid_change: TAEKILDRRVSEMRRQREEGLDSIRMLDDKIKFAQDNFSSVSIDGGPIEIVEKYDEEMEKLFYQNRKNKKMSQNDEQNEKIIEKNKLNGDQDHNDVMNRLEELEKLEQDNDEMEEAPIPKPFEVSNEDLQDLGKLEEVEEVEQDPTDKKLRFGMNERLLAQPGVTQKEMERLLDFLDTCDEESSDEEYDEDEEEGDDDEENLNNSVEELDSDDYAS/X
      C55B7.9b.1 VEP_consequence: 5_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: ?-505
        Exon_number: 1/7
      C55B7.9a.2 VEP_consequence: 5_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: ?-10
        Exon_number: 1/9
  Isolation: Mutagen: TMP/UV
  Genetics: Map: I
  Description: Phenotype: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
            Laboratory_evidence: FX
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson48
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson48
            Laboratory_evidence: FX
  Remark: 12824/12825-13470/13471 (646 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele