WormBase Tree Display for Variation: WBVar00250463

WBVar00250463 Name: Public_name: tm1471
    Other_name: F41G4.3d.2:c.-22+61_61-8del
      F41G4.3b.1:c.34-90_115-8del
      F41G4.3c.1:c.274-90_355-8del
      F41G4.3e.1:c.40-90_121-8del
      F41G4.3a.1:c.118-90_199-8del
      F41G4.3d.1:c.-21-90_61-8del
    HGVSg: CHROMOSOME_X:g.16817956_16818461del
  Sequence_details: SMap: S_parent: Sequence: F41G4
    Flanking_sequences: tgggagataagcggcggtggttcctgaaat ggaacctgaaacgtgttggttaacctggaa
    Mapping_target: F41G4
    Source_location: 7 CHROMOSOME_X 16817955 16818462 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm1471_external
      tm1471_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 1471
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00006067
    Transcript: F41G4.3c.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F41G4.3c.1:c.274-90_355-8del
        Intron_number: 2-3/8
        Exon_number: 3/9
      F41G4.3a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F41G4.3a.1:c.118-90_199-8del
        Intron_number: 3-4/9
        Exon_number: 4/10
      F41G4.3d.3 VEP_consequence: splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        Intron_number: 2/7
        Exon_number: 1-2/8
      F41G4.3e.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F41G4.3e.1:c.40-90_121-8del
        Intron_number: 1-2/6
        Exon_number: 2/7
      F41G4.3d.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F41G4.3d.2:c.-22+61_61-8del
        Intron_number: 1-3/8
        Exon_number: 2-3/9
      F41G4.3d.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F41G4.3d.1:c.-21-90_61-8del
        Intron_number: 1-3/8
        Exon_number: 2-3/9
      F41G4.3b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F41G4.3b.1:c.34-90_115-8del
        Intron_number: 2-3/8
        Exon_number: 3/9
  Isolation: Mutagen: TMP/UV
  Genetics: Map: X
  Description: Phenotype_not_observed: WBPhenotype:0000030 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. C. Hunter to the National Bioresource Project of Japan: normal growth Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000315 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment to the National Bioresource Project of Japan from Dr. M. Chalfie: non-Mec. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000518 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. C. Hunter to the National Bioresource Project of Japan: normal developement at 20C. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000625 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. K. Shen to the National Bioresource Project of Japan: normal synapse formation as determined by VAMP::YFP localization to presynaptic sites in HSNL. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: TV
  Remark: 12808/12809-13314/13315 (506 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele