WormBase Tree Display for Variation: WBVar00250477

WBVar00250477 Name: Public_name: tm1485
    Other_name: C18C4.10a.1:c.39-112_588del
      C18C4.10b.2:c.-25-112_525del
    HGVSg: CHROMOSOME_V:g.5578877_5579641del
  Sequence_details: SMap: S_parent: Sequence: C18C4
    Flanking_sequences: ttggttgaattgactagcattcatatcttc attaggtcgttcaataagttttgcgatagt
    Mapping_target: C18C4
    Source_location: 7 CHROMOSOME_V 5578876 5579642 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm1485_external
      tm1485_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 1485
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00002215
    Transcript: C18C4.10b.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C18C4.10b.2:c.-25-112_525del
        cDNA_position: ?-659
        CDS_position: ?-525
        Protein_position: ?-175
        Intron_number: 1-4/7
        Exon_number: 2-5/8
      C18C4.10a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C18C4.10a.1:c.39-112_588del
        cDNA_position: ?-650
        CDS_position: ?-588
        Protein_position: ?-196
        Intron_number: 2-4/7
        Exon_number: 3-5/8
      C18C4.10b.3 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-533
        CDS_position: ?-525
        Protein_position: ?-175
        Intron_number: 1-3/6
        Exon_number: 1-4/7
      C18C4.10b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-550
        CDS_position: ?-525
        Protein_position: ?-175
        Intron_number: 2-3/6
        Exon_number: 1-4/7
      C18C4.10c.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: ?-556
        CDS_position: ?-525
        Protein_position: ?-175
        Intron_number: 2-3/6
        Exon_number: 1-4/7
  Isolation: Mutagen: TMP/UV
  Genetics: Map: V
  Description: Phenotype: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Comment to the NBP from Dr. M. Barr: lost. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
    Phenotype_not_observed: WBPhenotype:0000102 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. K. Shen to the National Bioresource Project of Japan: unable to examine HSN synaptic phenotypes. Rare escapers show normal HSN vulaval presynaptic vesicle clusters (unc-86::SNB-1::YFP). Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0002535 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment from Dr. P. Sengupta to the National Bioresource Project of Japan: dyf+ in all sensory neurons. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
  Remark: 40118/40119-40883/40884 (765 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele