WormBase Tree Display for Variation: WBVar00251239

WBVar00251239 Name: Public_name: tm2338
    Other_name: Y43H11AL.3a.2:c.1428_1803-16del
      Y43H11AL.3a.1:c.1428_1803-16del
    HGVSg: CHROMOSOME_II:g.251865_252393del
  Sequence_details: SMap: S_parent: Sequence: Y43H11AL
    Flanking_sequences: ggagatctatctttcctgcaaaaaaaaagc tgattcatagtaacacttgaactctgtgtt
    Mapping_target: Y43H11AL
    Source_location: 7 CHROMOSOME_II 251864 252394 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm2338_external
      tm2338_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 2338
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00004166
    Transcript: Y43H11AL.3a.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y43H11AL.3a.2:c.1428_1803-16del
        cDNA_position: 1540-?
        CDS_position: 1428-?
        Protein_position: 476-?
        Intron_number: 8-9/28
        Exon_number: 8-9/29
      Y43H11AL.3a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y43H11AL.3a.1:c.1428_1803-16del
        cDNA_position: 1442-?
        CDS_position: 1428-?
        Protein_position: 476-?
        Intron_number: 7-8/27
        Exon_number: 7-8/28
  Isolation: Mutagen: TMP/UV
  Genetics: Map: II
  Description: Phenotype: WBPhenotype:0000216 Paper_evidence: WBPaper00038432
        Curator_confirmed: WBPerson712
        Remark: Animals exhibited extra A/PVM cells along with extra SDQ neurons. Defects were also observed for PHA/PHB, PLM, A/PQR and I2, other cell lineages that have either a sister or aunt that dies, but not lineages that do not. Paper_evidence: WBPaper00038432
            Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: zdIs5[Pmec-4::GFP; lin-15(+)] Paper_evidence: WBPaper00038432
              Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as 'sterile' by the National BioResource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
    Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as 'homozygous viable' by the National BioResource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
  Reference: WBPaper00038432
  Remark: 29763/29764-30292/30293 (529 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele