WormBase Tree Display for Variation: WBVar00252165

WBVar00252165 Name: Public_name: tm3496
    Other_name: T05A6.2a.1:c.548_*54+21del
      T05A6.2b.2:c.551_*54+21del
      T05A6.2b.1:c.551_*54+21del
      T05A6.2a.2:c.548_*54+21del
      T05A6.2c.1:c.469+712_469+1073del
    HGVSg: CHROMOSOME_II:g.7817976_7818337del
  Sequence_details: SMap: S_parent: Sequence: T05A6
    Flanking_sequences: ctgccgtttcgatgagtcgttcagtttcaa acatatgggttcaattcaaatcaatcacta
    Mapping_target: T05A6
    Source_location: 7 CHROMOSOME_II 7817975 7818338 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm3496_external
      tm3496_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 3496
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00000517
    Transcript: T05A6.2a.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: T05A6.2a.2:c.548_*54+21del
        cDNA_position: 595-?
        CDS_position: 548-?
        Protein_position: 183-?
        Intron_number: 5-7/7
        Exon_number: 5-7/8
      T05A6.2b.2 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: T05A6.2b.2:c.551_*54+21del
        cDNA_position: 581-?
        CDS_position: 551-?
        Protein_position: 184-?
        Intron_number: 5-7/7
        Exon_number: 5-7/8
      T05A6.2c.1 VEP_consequence: intron_variant
        VEP_impact: MODIFIER
        HGVSc: T05A6.2c.1:c.469+712_469+1073del
        Intron_number: 4/5
      T05A6.2b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: T05A6.2b.1:c.551_*54+21del
        cDNA_position: 695-?
        CDS_position: 551-?
        Protein_position: 184-?
        Intron_number: 6-8/8
        Exon_number: 6-8/9
      T05A6.2a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: T05A6.2a.1:c.548_*54+21del
        cDNA_position: 693-?
        CDS_position: 548-?
        Protein_position: 183-?
        Intron_number: 6-8/8
        Exon_number: 6-8/9
  Isolation: Mutagen: TMP/UV
  Genetics: Map: II
  Description: Phenotype: WBPhenotype:0001175 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comments to the National Bioresource Project of Japan: Dr. S. Boulton: 0.26% males Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0001493 Paper_evidence: WBPaper00034720
        Curator_confirmed: WBPerson2021
        Remark: The VPCs of cki-2 mutant animals undergo extra cell divisions prior to the L2/L3 molt Paper_evidence: WBPaper00034720
            Curator_confirmed: WBPerson2021
        EQ_annotations: Anatomy_term: WBbt:0007809 PATO:0000460 Paper_evidence: WBPaper00034720
                Curator_confirmed: WBPerson2021
    Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000643 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment to the National Bioresource Project of Japan from Dr. E.T. Kipreos: normal locomotion. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment to the National Bioresource Project of Japan from Dr. E.T. Kipreos: fertile. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
  Reference: WBPaper00034720
  Remark: 16368/16369-16730/16731 (362 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele