WormBase Tree Display for Variation: WBVar00252636

WBVar00252636 Name: Public_name: tm4085
    Other_name: Y74C9A.2a.3:c.50-192_103del
      Y74C9A.2a.2:c.50-192_103del
      Y74C9A.2a.1:c.50-192_103del
    HGVSg: CHROMOSOME_I:g.14759_15004del
  Sequence_details: SMap: S_parent: Sequence: Y74C9A
    Flanking_sequences: aaaactacattaattctttaaatgacacgc aactgtacagtctggagaaagagaacggag
    Mapping_target: Y74C9A
    Source_location: 7 CHROMOSOME_I 14758 15005 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm4085_external
      tm4085_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00056064
      WBStrain00056096
    Laboratory: FX
      OJ
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 4085
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00022276
    Transcript: Y74C9A.2a.3 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y74C9A.2a.3:c.50-192_103del
        cDNA_position: ?-193
        CDS_position: ?-103
        Protein_position: ?-35
        Intron_number: 3/5
        Exon_number: 4/6
      Y74C9A.2a.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y74C9A.2a.1:c.50-192_103del
        cDNA_position: ?-193
        CDS_position: ?-103
        Protein_position: ?-35
        Intron_number: 3/5
        Exon_number: 4/6
      Y74C9A.2a.2 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y74C9A.2a.2:c.50-192_103del
        cDNA_position: ?-126
        CDS_position: ?-103
        Protein_position: ?-35
        Intron_number: 2/4
        Exon_number: 3/5
  Isolation: Mutagen: TMP/UV
  Genetics: Map: I
  Description: Phenotype: WBPhenotype:0000031 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Comment to the National Bioresource Project of Japan from Dr. M. Nonet: Gro. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000204 Paper_evidence: WBPaper00042242
        Curator_confirmed: WBPerson557
        Remark: Mutant shows mild defects in aBoc steps. Paper_evidence: WBPaper00042242
            Curator_confirmed: WBPerson557
      WBPhenotype:0000205 Paper_evidence: WBPaper00042242
        Curator_confirmed: WBPerson557
        Remark: Mutant shows a nearly complete loss of the expulsion of gut contents (Exp). Measured as Exp per cycle (Exp frequency). Paper_evidence: WBPaper00042242
            Curator_confirmed: WBPerson557
      WBPhenotype:0000625 Paper_evidence: WBPaper00064204
        Curator_confirmed: WBPerson7196
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
      WBPhenotype:0000996 Paper_evidence: WBPaper00042242
        Curator_confirmed: WBPerson590
    Phenotype_not_observed: WBPhenotype:0000157 Paper_evidence: WBPaper00042242
        Curator_confirmed: WBPerson557
  Reference: WBPaper00042242
    WBPaper00065757
    WBPaper00064204
  Remark: 14698/14699-14944/14945 (246 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele