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WormBase Tree Display for Variation: WBVar00253111

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Name Class

WBVar00253111EvidencePaper_evidenceWBPaper00032907
NamePublic_nametr117
Other_nameF55C7.7i.1:c.4003G>A
CE36937:p.Glu1335Lys
F55C7.7i.2:c.4003G>A
CE19465:p.Glu1335Lys
F55C7.7b.1:c.4003G>A
CE19464:p.Glu1335Lys
F55C7.7a.1:c.4003G>A
HGVSgCHROMOSOME_I:g.4022142C>T
Sequence_detailsSMapS_parentSequenceF55C7
Flanking_sequencesccgagaacgacacggattggagatcaataacagattgcgagtctcttgataaagcctgttca
Mapping_targetF55C7
Type_of_mutationSubstitutiongaPaper_evidenceWBPaper00032907
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
LaboratoryRP
StatusLive
AffectsGeneWBGene00006805
TranscriptF55C7.7i.1 (12)
F55C7.7b.1 (12)
F55C7.7a.1 (12)
F55C7.7i.2 (12)
IsolationMutagenEMS
GeneticsInterpolated_map_positionI-1.85849
DescriptionPhenotypeWBPhenotype:0000324Paper_evidenceWBPaper00032907
Curator_confirmedWBPerson712
WBPhenotype:0000643Paper_evidenceWBPaper00032907
Curator_confirmedWBPerson712
WBPhenotype:0001226Paper_evidenceWBPaper00032907
Curator_confirmedWBPerson712
RemarkAnimals exhibit commissural axon guidance defects.Paper_evidenceWBPaper00032907
Curator_confirmedWBPerson712
WBPhenotype:0001930Paper_evidenceWBPaper00032907
Curator_confirmedWBPerson712
RemarkAnimals were isolated based on altered or fewer muscle arms, observed by an altered pattern of trIs25 reporter expression, which expresses membrane-anchored YFP in select muscles of only the distal row of body wall muscles. This defect can be rescued by muscle-expressed UNC-73, but not by neuronal-expressed UNC-73. Mutants exhibit non-allelic non-complementation with unc-40(n234) and unc-40(tr121).Paper_evidenceWBPaper00032907
Curator_confirmedWBPerson712
Phenotype_assayGenotypeRP112Paper_evidenceWBPaper00032907
Curator_confirmedWBPerson712
ReferenceWBPaper00032907
MethodSubstitution_allele