WormBase Tree Display for Variation: WBVar00275059

WBVar00275059 Evidence: Paper_evidence: WBPaper00031440
  Name: Public_name: vr11
    Other_name: K02B9.1.1:c.924_1286del
      CE16206:p.Ser309_Ter429delextTer?
    HGVSg: CHROMOSOME_X:g.13928235_13928640del
  Sequence_details: SMap: S_parent: Sequence: K02B9
    Flanking_sequences: cgggaatcaacagttccaaatgaatcaaag ctggcggaagacgatgcaaatgcagaatcg
    Mapping_target: K02B9
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00047719
    Laboratory: YL
    Status: Live
  Affects: Gene: WBGene00010492
    Transcript: K02B9.1.1 (11)
    Interactor: WBInteraction000503447
      WBInteraction000534816
  Genetics: Interpolated_map_position: X 15.4383
  Description: Phenotype: WBPhenotype:0000436 Paper_evidence: WBPaper00031440
        Curator_confirmed: WBPerson2021
        Remark: Mutant embryos had an expanded domain of MES-1 localization to both sides of the germline blastomere that bordered cells other than the endodermal blastomere and sometimes became diffuse Paper_evidence: WBPaper00031440
            Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00031440
          Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00031440
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000003 PATO:0000460 Paper_evidence: WBPaper00031440
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00031440
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: MES-1 antibody staining Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
          Temperature: 25C Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000823 Paper_evidence: WBPaper00031440
        Curator_confirmed: WBPerson2021
        Remark: meg-1 mutants have a severely underproliferated germline phenotype Paper_evidence: WBPaper00031440
            Curator_confirmed: WBPerson2021
        Penetrance: Incomplete: Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00031440
          Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00031440
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000041 PATO:0000460 Paper_evidence: WBPaper00031440
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00031440
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: DAPI staining Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
          Temperature: 25C Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001504 Paper_evidence: WBPaper00031440
        Curator_confirmed: WBPerson2021
          WBPerson557
        Remark: Hermaphrodites exhibit maternal-effect sterility Paper_evidence: WBPaper00031440
            Curator_confirmed: WBPerson2021
        Penetrance: Incomplete: Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
        Recessive: Paper_evidence: WBPaper00031440
          Curator_confirmed: WBPerson2021
        Variation_effect: Probable_null_via_phenotype: Paper_evidence: WBPaper00031440
            Curator_confirmed: WBPerson2021
        EQ_annotations: Life_stage: WBls:0000057 PATO:0000460 Paper_evidence: WBPaper00031440
                Curator_confirmed: WBPerson2021
        Temperature_sensitive: Heat_sensitive: Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
        Maternal: Strictly_maternal: Paper_evidence: WBPaper00031440
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Temperature: 25C Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson2021
            15 Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson557
            20 Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson557
            25 Paper_evidence: WBPaper00031440
              Curator_confirmed: WBPerson557
  Reference: WBPaper00031440
  Method: Deletion_allele