WormBase Tree Display for Variation: WBVar00275386
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| WBVar00275386 | Evidence | Paper_evidence | WBPaper00004264 | |||||
|---|---|---|---|---|---|---|---|---|
| Name | Public_name | ye8 | ||||||
| Sequence_details | SeqStatus | Pending_curation | ||||||
| Variation_type | Allele | |||||||
| Origin | Species | Caenorhabditis elegans | ||||||
| Laboratory | HY | |||||||
| Status | Live | |||||||
| Affects | Gene | WBGene00000267 | ||||||
| Description | Phenotype | WBPhenotype:0000673 | Paper_evidence | WBPaper00004264 | ||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Animals have robust but lower than wild-type brood sizes. | Paper_evidence | WBPaper00004264 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0002060 | Paper_evidence | WBPaper00004264 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Produces a brood when grown in the presence of Bt toxin Cry5B. The intestines of mutants fed Bt-produced toxin have intestinal morphology often indistinguishable from that of healthy wild-type intestine not exposed to toxin. Mutants are resistant to Cry5B-induced lethality. Unlike toxin-exposed wild-type animals, toxin-exposed mutants show only a modest reduction in fertility. Similar resistance is observed for animals exposed to E. coli produced Cry5B toxin. Mutants are similarly sensitive to Cry6A. | Paper_evidence | WBPaper00004264 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Recessive | Paper_evidence | WBPaper00004264 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Affected_by | Molecule | WBMol:00005329 | Paper_evidence | WBPaper00004264 | ||||
| Curator_confirmed | WBPerson712 | |||||||
| Phenotype_not_observed | WBPhenotype:0000072 | Paper_evidence | WBPaper00004264 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Animals appear morphologically normal. | Paper_evidence | WBPaper00004264 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000517 | Paper_evidence | WBPaper00004264 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Animals behave similarly to wild-type. | Paper_evidence | WBPaper00004264 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000676 | Paper_evidence | WBPaper00004264 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | Animals develop from embryos to adults at the normal wild-type rate. | Paper_evidence | WBPaper00004264 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Reference | WBPaper00004264 | |||||||
| Method | Allele |
