WormBase Tree Display for Variation: WBVar00275446
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WBVar00275446 | Evidence | Paper_evidence | WBPaper00003496 | |||||
---|---|---|---|---|---|---|---|---|
Name | Public_name | yw23 | ||||||
Sequence_details | SeqStatus | Pending_curation | ||||||
Variation_type | Allele | |||||||
Origin | Species | Caenorhabditis elegans | ||||||
Strain | WBStrain00008401 | |||||||
WBStrain00008402 | ||||||||
Laboratory | HG | |||||||
Status | Live | |||||||
Affects | Gene | WBGene00000091 | ||||||
Interactor | WBInteraction000519027 | |||||||
WBInteraction000519028 | ||||||||
WBInteraction000519029 | ||||||||
WBInteraction000519030 | ||||||||
WBInteraction000519031 | ||||||||
Description | Phenotype | WBPhenotype:0000043 | Paper_evidence | WBPaper00003496 | ||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mutants have a somewhat increased development time. Hermaphrodites of HG231 age-2(yw23) developed more slowly than N2 hermaphrodites, requiring about 25% more time to begin egg laying at both 20C and 25C. | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
Recessive | Paper_evidence | WBPaper00003496 | ||||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000061 | Paper_evidence | WBPaper00003496 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mutants have an increased life span. In a total of 29 trials, the age-2 mutant exhibited a mean increase of ~17% in median longevity. It exhibited a mean increase in maximum longevity of ~21% compared to N2 animals. In a population of 150 HG231 animals studied for survival and mortality rates, mean and median life span was 22% longer than that for N2. HG231 showed a slightly shorter mortality-rate doubling time than N2, but also showed a lower initial (Gompertz) mortality rate. A slightly faster rate of increase of mortality was observed late in its life span, compared to N2. | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
Recessive | Paper_evidence | WBPaper00003496 | ||||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001384 | Paper_evidence | WBPaper00003496 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mutants have somewhat reduced fertility. The outcrossed strain, HG231 age-2(yw23), showed much higher fertility at 25C than did non-outcrossed HG23, but less than half that of N2. Fertility of HG231 at 20C was closer to that of N2. | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
Temperature_sensitive | Heat_sensitive | 25 | Paper_evidence | WBPaper00003496 | ||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0001481 | Paper_evidence | WBPaper00003496 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mutants have no reduction in swimming rate. The swimming rate of HG231 age-2(yw23) was slightly (5%) greater than that of N2. | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
Phenotype_not_observed | WBPhenotype:0000012 | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mutants were not dauer constitutive at 27C. | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000643 | Paper_evidence | WBPaper00003496 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mutants appeared normal. | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000648 | Paper_evidence | WBPaper00003496 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mutants appeared normal. | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0000659 | Paper_evidence | WBPaper00003496 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mutants appeared normal, including pharyngeal pumping. | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
WBPhenotype:0004001 | Paper_evidence | WBPaper00003496 | ||||||
Curator_confirmed | WBPerson712 | |||||||
Remark | Mutants appeared normal. | Paper_evidence | WBPaper00003496 | |||||
Curator_confirmed | WBPerson712 | |||||||
Reference | WBPaper00003496 | |||||||
Method | Allele |