WormBase Tree Display for Variation: WBVar02152964

WBVar02152964 Name: Public_name: ju1659
    Other_name: F11C1.5a.1:c.3_5333del
      F11C1.5a.2:c.3_5333del
      CE41311:p.MetIleThrArgValSerLeuLeuArgLeuGlnHisAlaArgLysValLeuThrThrThrGlyIleGlnGluSerPheAsnLysThrIlePheIleValAsnIleGlnHisLeuLeuAlaProAsnHisArgArgTerLeuSerGluValLeuValTyrAsnPheLysMetGlnArgThrGlnThrLeuSerGlnProSerMetGlyArgLysThrIleProHisArgIleCysSerHisIleTerAspGlySerPheLysLysThrAsnTerSerLysThrCysPheCysTrpGluCysArgGluLysSerAspTrpAsnLeuSerTerAspIleTrpTerAspPheIleProIleLysLeuTerLysTerLysAspIleGlyTyrLeuTrpValSerPheProGlnAsnValLeuIlePheTerValSerIleAsnHisLysAsnValAsnPheLeuGluGlnPheValGluMetAsnAlaSerPheLeuIlePheValHisAlaPheAsnMetLysGlyGlyTerLeuLeuPheArgLysLeuLysHisPheGlyTrpAsnGluThrAsnLysTyrGlnLeuTerLeuLeuLysValAsnPheLeuTerLysThrSerIleLysTerSerAsnAsnPheThrValPheAsnLysIleIleLeuLysGluAlaThrAsnArgGluPheGluTyrLeuProIleThrArgAspThrThrGluAlaAspIleLysGlnArgArgGluIleArgAspGlyThrAlaTyrTyrThrAspLeuValSerThrPhePheLysAsnLeuArgPheGlnPheLeuIleHisSerValArgPheValGlnHisTerLysGluGluCysTerTerLeuMetValTrpLysGluProAsnGluThrCysPheGlnSerTerThrIlePheTrpLysIleGluLysCysAsnTrpThrMetGluAspPheTerTerSerMetThrAsnThrMetSerTerArgTerAsnThrMetLysArgHisTerArgArgTrpGluTrpSerGluPheLeuLysThrSerMetSerTerProLeuValPheProTyrGlnAspSerArgGluIleLeuTrpIleArgArgSerGluAlaAspSerAsnAlaGluIlePheArgSerTyrArgSerThrHisPheTrpAsnLysArgSerSerLeuLeuGlnThrLeuValArgGlnIleLeuThrIleTerTyrProLeuCysMetProIleIleArgLysArgGlnLeuGlnAspGlnGluSerAlaGlnLeuSerTerArgIleHisTerArgPheGlyTerValTyrThrIlePheGluSerAspLysArgArgIleGluIleAspLeuLysLeuTyrTerArgPheAsnPheGlnAsnGluAsnProSerTyrSerAlaGlyGluIleValAsnPheSerTyrProAlaLysGluValLeuSerAspSerGluLysAspLeuIleAsnThrPheLysThrLysPheGluLeuValSerTyrAsnTyrValSerGlnSerIleGlnAsnIlePheCysArgValLeuMetAsnAlaProGluAsnTerLysArgThrValLeuTyrIleArgPheLysPheLeuLeuThrArgGluArgSerArgTerSerCysGlnHisHisHisIleLeuLeuHisLeuArgLeuLeuGlyPheGlnProGlnSerLysLysIleTerSerArgIleLeuLeuTerHisPheArgLysGluThrLeuSerTerLeuAspGlnLysAlaLeuGlyAsnArgGluSerLeuAlaAsnPheHisAspValSerIleSerIleMetSerGlnTrpPheCysIleLysIleTerThrProGluSerLeuSerAsnAlaAspIleTerLysLysMetAlaIleGlnPheGlyLysThrArgPheLeuTerLeuGlnGlnGluMetGluMetSerValPheTrpMetValSerLysTrpCysIleLeuValLeuLeuCysHisSerArgSerTerPheIleIleGluAspLeuIleTyrGlnMetGluIleValLeuLeuGluArgLysSerPheTerLeuLeuTrpLysGluMetGluLeuMetLysGlnGlnTerThrLysGlyMetTrpValLeuThrLysTyrSerAspTyrAsnLeuAspLysIlePheGlnAsnCysArgLeuLysSerHisMetIleLeuAsnLeuPheIleTerAsnThrIleAsnThrTerAspThrAsnSerTyrPheIleGlnPheTerTerValTerCysPheLeuLysGlnIlePheGluThrThrTerPheLeuTrpLysGlnLeuTerHisIleGlySerArgPhePheLeuValPheArgTyrTyrTerGlyTrpGlnIleGluHisLeuProAlaThrArgSerCysGluAsnTerArgLysTerIleLeuLysLysHisLeuTerLysThrTerHisAlaValPheGlnProTyrValLeuGlnPheSerArgLysArgPheValAlaAsnLeuLeuThrIleAsnAsnGlnIlePheArgGlyValPheGlnIleProAspSerPheArgValLeuPheValGlyGluSerGlnSerLysGluHisLysTrpIleAsnGluAsnValLeuSerIleLeuProPheTyrThrValProAsnLeuSerLeuSerGluGlnMetSerIleIleSerGluIleThrHisGlySerAsnThrGluSerValAspLysLeuIleLysPheValGlnThrIleLysAsnSerAsnAspAlaGlyValArgPheLeuGluTyrLeuTyrTerPheLeuLysIleValPheValPheProValLysLysTyrCysAsnLysPheValAlaSerSerIleAspSerHisCysLysThrArgSerAspAlaAlaGlyThrLeuGluArgAlaCysArgLysSerCysSerLeuLysValProProThrAsnHisGlnGlyAsnIleArgThrTerAlaGlnHisCysLysArgLeuTerTerTyrTyrTyrSerHisLysGlyGluTerGluValProTerHisAspSerSerLysHisTyrLysSerGlyArgTerSerSerTyrSerLysCysAlaIleProProTerTerAlaAlaArgArgAsnSerArgGlyHisGlyLysArgHisGluThrGlyLysSerPheAlaPheAspArgTerProArgSerArgLysLysTerThrHisTerTerValProSerProAsnLysSerThrGluThrValHisAlaAlaSerGlnValSerValLysValMetPheSerAsnLeuArgIleIlePheArgAspThrThrValGlnThrLeuThrMetGlnThrValValGluAsnGlyIleIleArgHisGluAspSerAlaLeuValLysAlaAlaArgSerGlyGlnValSerIleLysSerThrAspProLysAsnLeuLeuIleArgAlaLeuThrAlaAsnLeuIleAsnTerThrPheAspSerProAsnSerLeuSerGlyIleTerIleGlnIleTerLysAlaIlePheTerGlyTyrLeuIlePhePheArgPheLeuTerLeuMetLysLeuThrLysArgLeuTyrThrTerSerLeuPheTerLysValPheSerThrGlnGluHisTrpCysLeuGluMetGlyGluHisPheValGlnGlnValLeuSerGlnLysLeuIleLysGlnMetIleAlaLeuPheGlnPheIleProThrLeuGluLeuSerCysLeuProThrAspLeuAspSerHisSerLeuValIleArgHisGlnLysLeuPhePheSerIlePheLeuProPheArgGlnGlnPheValCysCysThrTrpTerSerValCysAsnSerHisAspTerSerProArgLysArgTerTerThrArgAsnAspTerGluIleTrpThrAsnGlySerCysLysAsnSerTerProThrPheAsnAsnPheGlnArgAlaAlaArgLysAsnTerProArgThrPheThrValSerLeuLeuAspSerArgThrCysTerTyrCysSerProLeuGlnCysGluPheAsnTerHisPheValSerLysLysAsnTerLysTyrIlePheLysGluPheProThrAspProLeuProGluValCysArgAsnValPheAspPheAspSerTyrSerGluAspThrIleAlaThrIleHisGluValPheGlnLysHisGlyValProLeuGlyTerSerLeuPheCysIleLeuTyrPheIleIleGlyCysIleValGluLeuPheLeuArgTerTerThrIleLeuLeuValPheLeuLeuThrPheTerLysPheSerGlyValIleArgThrGlyGluSerLeuSerIleMetGluArgIleProLeuGlyGluMetLysThrIleGlyLysTrpSerArgGlnLysValGluPheProLysSerTyrGlyPheLysThrProValAlaValGluIleGluArgProGluLysMetGluPheGlyLeuArgLysLeuAspLysGlnSerAsnArgAsnAsnValPheSerGluLeuHisCysValTrpLysLeuProThrAspGluSerAsnIleIleSerAspGlyIleArgIleAsnAspAspLeuLeuValAlaSerValAsnProProArgLeuTyrHisCysLysAspPheMetAspThrGluSerValIleLeuLeuIleLysAsnTerIleAsnSerPheLysAsnIleTyrAlaLeuGluAsnLeuLysAsnValGluPheLysLysSerSerTerThrLeuTerLeuSerPheGluPheTyrGlyValThrGlnValMetLeuArgAsnValPheLysTyrIleTyrAspValThrThrValLeuLysTyrMetPheAsnValPheTyrAsnSerCysAspValIlePheLeuTyrIleLeuIlePheGlnHisTyrLeuAsnAsnProIleThrLysLysPheLeuIleLeuTyrGlnPheSerGluGlnAspLeuPhePheProAsnProHisPheArgPheSerGlyTerArgAsnGlnHisThrGlnAspTyrProSerPheSerCysAsnTerGlnThrThrAsnTerThrSerIleSerTrpTrpArgGlnCysAlaAlaThrArgArgArgGlyMetProPheProIleLysTyrValGluLeuLeuAspPheArgArgThrSerGlnArgSerSerAlaCysProThrLysTrpArgLeuLeuLeuGlnSerLysArgValTrpValLysArgLeuGluLeuValSerAlaCysCysLysLeuTyrSerLysTyrLeuTyrPheSerValTyrArgPheGlnLeuPheMetGluIleIleLysSerThrLysGlnSerArgPheAlaLeuTerValValCysIleTerThrGlnSerPheLeuGlnCysMetCysPheSerGlyGlyArgGluMetLeuValTyrThrAspGluLysHisGlyValThrValGlnAsnGlyThrValProPheAsnIleLysArgValPheAlaSerAlaProGlnGlnTrpThrValValSerMetValLysTerTyrAsnIleTyrSerGlySerIleIleThrValLeuLeuGlyLysTerGluLeuSerSerGluGlyGlyThrArgLysPheTyrPheGlyGluAsnTerGlnArgPheGlyArgArgProArgTyrGlyCysAsnLysValGlyGlnGluCysAsnAspPheSerCysArgAlaIleLeuLeuCysSerArgLysProCysTerLeuPheLeuSerThrAsnAsnIleGluCysLysLeuAsnPheGlnSerGlySerValSerGlyValLeuArgLysLysSerGluAsnThrPheHisLysArgProTyrSerPheThrAspAspArgIleAlaAlaAsnAspValSerArgGluAsnAlaPheLeuGlySerThrLeuValArgAlaValProGlyPheMetThrProThrGluCysValGluGluSerGluLeuTyrTyrTyrIlePheLysCysPheTerIleLysSerSerCysValLeuAsnLysTyrAsnGluPheIleLysIleLeuGlyTrpArgGluAsnProValLeuPhePheAsnHisLeuPheLeuLysAlaAsnSerAsnTerLysSerValIleTyrSerIleMetPheAsnAsnValLeuProThrTerTyrIleGluCysLeuPheTyrArgAsnLysAlaIleArgLeuTyrTrpIleProArgAspAsnArgTyrGlyLysLysGluAsnLeuLeuCysThrGlySerAlaTerTrpGluTyrGlnPheIleProValSerPheIleThrGlyAlaThrCysSerIleLeuIlePheArgAspTrpValAlaSerIleThrLysSerAlaPheHisIleValProTrpAspAsnAspLysValLeuThrValAspSerSerGlySerIleArgSerPheGluLeuArgMetSerThrLeuGluLysSerPheAspAspTrpLysArgMetThrGlyGlyAlaAspAspGluLysLeuArgMetGluPheAspArgLysProAspAspValAspPheAsnLysLeuAspGluProLysLeuGlyLysTerValIleValTyrArgSerAlaSerSerThrTerPheLeuSerGlySerThrProThrMetHisLeuIleThrValGluIleAsnGlyTrpGluGluLeuValAspThrIleLeuGlnValSerGluGluLeuGluGlyArgSerAspLeuThrGlnValMetMetSerIleLysCysGlnIleLeuLeuSerAsnLysSerArgSerThrTyrTerLysLysProGlyArgLeuGlnLysTerSerMetGlnArgAsnTerGlyTyrValThrValPheLeuTerGluValLysTerMetPheTerGlyAsnGlnHisValGlyValTerArgArgCysLeuTerLysSerValGluGlnSerSerSerSerIleLysLysThrSerIleCysAspTerProIleGlyGlyThrLeuAsnSerThrLeuTerPhePheLysProTerPheLeuGlyLysGluLysArgLysArgMetAspLysAlaSerAsnTerArgArgPheGlyTerArgLysIleAspTerArgSerHisArgArgAlaGluTyrLeuGlnValAsnLeuValIleLeuLysIleThrLysCysLysPheProThrSerArgArgArgIleAspLysValProAspProGlyAlaProGlnThrLysProLysArgLeuLysValCysLeuAspValSerGlySerMetTyrArgPheAsnGlyTyrAspGlnArgLeuValLysSerLeuGluAlaAlaLeuMetThrMetThrAlaLeuAspGlyLysThrAspLysValGlnValCysAspSerLysLysPheLeuLeuLysLysProLysLysLeuValHisAspTyrSerTerThrSerAsnIleIlePheSerThrThrLeuLeuAspIleLeuGluThrLeuHisAlaCysHisLeuTerArgProIleIleIleProLysThrThrLysAsnValTrpIleHisTerAsnAlaTerLeuArgIleArgArgTerTerSerPheGlnLeuLeuSerValTerIleAsnAlaPheIlePheSerThrAlaSerValValThrIleArgTerArgValTyrAsnLeuGlnSerLysAsnTrpProGlnArgLysMetIleLeuMetLysProLeuSerPheTrpCysGlnMetLeuIleTrpLysGlyLysSerPheCysLysLeuAsnArgValAspThrLeuIleGlyPhePheIleIlePheArgTyrGlyIleGlnProLysGluLeuLysAspAlaMetAlaLysGluProAsnIleAsnSerPheValIlePheIleGlySerLeuSerAspGluAlaAspGlnLeuGlnArgGluLeuProVal1_?1778
    HGVSg: CHROMOSOME_X:g.12991501_12999489del
  Sequence_details: SMap: S_parent: Sequence: F11C1
    Flanking_sequences: ttcaggtaaaaaatacaggttttctcccat tggaaaagcttttgttttaaaagacacttc
    Mapping_target: F11C1
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Engineered_allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00047734 Paper_evidence: WBPaper00059749
    Laboratory: CZ
    Production_method: CRISPR_Cas9
    Status: Live
  Affects: Gene: WBGene00008694
    Transcript: F11C1.5e.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        cDNA_position: 32-?
        CDS_position: 3-?
        Protein_position: 1-?
        Intron_number: 2-12/13
        Exon_number: 2-14/14
      F11C1.5a.2 (11)
      F11C1.5a.1 (11)
  Possibly_affects: WBGene00008694 Paper_evidence: WBPaper00059749
      Remark: CGC_name vwa-8
  Description: Phenotype_not_observed: WBPhenotype:0000062 Paper_evidence: WBPaper00059749
        Curator_confirmed: WBPerson712
        Remark: vwa-8(ju1659) mutants are homozygous viable, and indistinguishable from wild type in gross phenotypes such as body size, brood size, growth rate and movement. Paper_evidence: WBPaper00059749
            Curator_confirmed: WBPerson712
      WBPhenotype:0000231 Paper_evidence: WBPaper00059749
        Curator_confirmed: WBPerson712
        Remark: vwa-8(ju1659) mutants are homozygous viable, and indistinguishable from wild type in gross phenotypes such as body size, brood size, growth rate and movement. Paper_evidence: WBPaper00059749
            Curator_confirmed: WBPerson712
      WBPhenotype:0000643 Paper_evidence: WBPaper00059749
        Curator_confirmed: WBPerson712
        Remark: vwa-8(ju1659) mutants are homozygous viable, and indistinguishable from wild type in gross phenotypes such as body size, brood size, growth rate and movement. Paper_evidence: WBPaper00059749
            Curator_confirmed: WBPerson712
      WBPhenotype:0000673 Paper_evidence: WBPaper00059749
        Curator_confirmed: WBPerson712
        Remark: vwa-8(ju1659) mutants are homozygous viable, and indistinguishable from wild type in gross phenotypes such as body size, brood size, growth rate and movement. Paper_evidence: WBPaper00059749
            Curator_confirmed: WBPerson712
      WBPhenotype:0000676 Paper_evidence: WBPaper00059749
        Curator_confirmed: WBPerson712
        Remark: vwa-8(ju1659) mutants are homozygous viable, and indistinguishable from wild type in gross phenotypes such as body size, brood size, growth rate and movement. Paper_evidence: WBPaper00059749
            Curator_confirmed: WBPerson712
  Reference: WBPaper00059749
  Remark: [2020-06-08T01:26:50.588Z WBPerson712] New Variation: WBPaper00059749 vwa-8(ju1659) deletes 7989bp. The start and stop codons of the F11C1.5a.1 isoform Curator_confirmed: WBPerson712
  Method: Engineered_allele