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WormBase Tree Display for Variation: WBVar02156836

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Name Class

WBVar02156836NamePublic_namexb6
Sequence_detailsSeqStatusPending_curation
OriginSpeciesCaenorhabditis elegans
StatusLive
Possibly_affectsWBGene00006999Paper_evidenceWBPaper00062008
RemarkCGC_name zyx-1
DescriptionPhenotypeWBPhenotype:0000978Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
RemarkWe observed little difference between the two genotypes in terms of entry time and exit time, but the dwell time was significantly longer in the zyx-1 deletion than in the wild type (Fig. 1E-G).Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000518Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
RemarkThe deletion animals did not exhibit any overt developmental, movement, or growth phenotypes.Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
WBPhenotype:0000520Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
RemarkThe deletion animals did not exhibit any overt developmental, movement, or growth phenotypes.Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
WBPhenotype:0000643Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
RemarkThe deletion animals did not exhibit any overt developmental, movement, or growth phenotypes.Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
WBPhenotype:0001659Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
RemarkAge matched, young adult zyx-1(xb6) and N2 animals were scored for spermathecal occupancy using differential interference contrast (DIC) microscopy. No statistically significant increase in spermathecal occupancy was observed (Fig. 1C). While a small piece of an oocyte was observed in the zyx-1(xb6) worms, this was also observed in our N2 control.Paper_evidenceWBPaper00062008
Curator_confirmedWBPerson712
ReferenceWBPaper00062008
Remark[2021-11-02T20:38:48.506Z WBPerson712] New Variation: WBPaper00062008 zyx-1 we deleted zyx-1 using CRISPR genome editing. The resulting deletion allele, zyx-1(xb6), is a 13,503 bp deletion with a 12 bp insertion, which removes the entire coding sequence of F24G4.3a (Fig. 1A).Curator_confirmedWBPerson712