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WormBase Tree Display for WBProcess: WBbiopr:00000010

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Name Class

WBbiopr:00000010Public_nameDefecation
SummaryIn C. elegans the expulsion of intestinal contents occurs every 45-50 seconds. This cycle is characterized by a pattern of muscle contractions under both muscle and neuronal control. The steps of the defecation cycle are a posterior body contraction (pBoc), an anterior body contraction (aBoc), and the final expulsion step (Exp) where the enteric muscles contract, opening the anus and allowing the intestinal contents to be released. Each step is independently controlled as mutations exist that affect one step but do not alter the timing or occurrence of the other. Further, Ca++ oscillations in the intestine, rather than neuronal stimulation, have been shown to control the initiating pBoc step. The contractions of the enteric muscles are controlled by GABA motor neurons AVL and DVB through an excitatory GABA-gated cation channel. The periodicity of the cycle is influenced by the presence of food, is temperature compensated, and can be reset by mechanosensory input.
Related_topicSpecialisation_ofWBbiopr:00000043
WBbiopr:00000040
Involved_entityGeneWBGene00000089Paper_evidenceWBPaper00001256
WBGene00000088Paper_evidenceWBPaper00001256
WBGene00004038Paper_evidenceWBPaper00026831
WBGene00001373Paper_evidenceWBPaper00001256
WBPaper00006173
WBGene00006454Paper_evidenceWBPaper00001256
WBGene00000084Paper_evidenceWBPaper00001256
WBGene00002173Paper_evidenceWBPaper00026831
WBGene00001133Paper_evidenceWBPaper00001256
WBGene00006782Paper_evidenceWBPaper00001759
WBGene00000085Paper_evidenceWBPaper00001256
WBGene00001177Paper_evidenceWBPaper00001256
WBPaper00026831
WBGene00006784Paper_evidenceWBPaper00006173
WBGene00003941Paper_evidenceWBPaper00001256
WBGene00001375Paper_evidenceWBPaper00001256
WBGene00000943Paper_evidenceWBPaper00001256
WBGene00000895Paper_evidenceWBPaper00024671
WBGene00006762Paper_evidenceWBPaper00001759
WBPaper00001256
WBGene00006766Paper_evidenceWBPaper00001759
WBGene00006779Paper_evidenceWBPaper00001759
WBPaper00001937
WBGene00006783Paper_evidenceWBPaper00001759
WBPaper00001256
WBGene00000086Paper_evidenceWBPaper00001256
WBGene00001374Paper_evidenceWBPaper00001256
WBGene00006755Paper_evidenceWBPaper00001256
WBGene00006769Paper_evidenceWBPaper00001256
InteractionWBInteraction000050597
WBInteraction000050598
WBInteraction000052169
WBInteraction000052170
WBInteraction000576759
WBInteraction000576760
WBInteraction000576761
WBInteraction000576762
WBInteraction000576763
WBInteraction000576764
WBInteraction000576765
WBInteraction000576767
Anatomy_termWBbt:0003843Paper_evidenceWBPaper00002272
WBbt:0004292Paper_evidenceWBPaper00002272
WBbt:0004822Paper_evidenceWBPaper00002272
WBbt:0005364Paper_evidenceWBPaper00002272
WBbt:0005748Paper_evidenceWBPaper00002272
WBbt:0005772Paper_evidenceWBPaper00002272
WBbt:0005773Paper_evidenceWBPaper00002272
WBbt:0005796Paper_evidenceWBPaper00002272
WBbt:0005798Paper_evidenceWBPaper00002272
WBbt:0005820Paper_evidenceWBPaper00002272
WBbt:0006804Paper_evidenceWBPaper00002272
Associated_withPhenotypeWBPhenotype:0000156
WBPhenotype:0000157
WBPhenotype:0000204
WBPhenotype:0000205
WBPhenotype:0000207
WBPhenotype:0000208
WBPhenotype:0000209
WBPhenotype:0000210
WBPhenotype:0000211
WBPhenotype:0000246
WBPhenotype:0000380
WBPhenotype:0000391
WBPhenotype:0000410
WBPhenotype:0000525
WBPhenotype:0000564
WBPhenotype:0000650
WBPhenotype:0000651
WBPhenotype:0000993
WBPhenotype:0000994
WBPhenotype:0000996
WBPhenotype:0001091
WBPhenotype:0001092
WBPhenotype:0001201
WBPhenotype:0001476
WBPhenotype:0001641
WBPhenotype:0001791
WBPhenotype:0001793
GO_termGO:0030421
GO:0035882
ReferenceWBPaper00001256
WBPaper00001759
WBPaper00001937
WBPaper00002272
WBPaper00006173
WBPaper00024671
WBPaper00026831
WBPaper00031264