WormBase Tree Display for Expr_pattern: Expr10537
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| Expr10537 | Expression_of | Gene | WBGene00006412 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006412 | |||
| Expression_data | Anatomy_term | WBbt:0006840 | Certain | |
| GO_term | GO:0030425 | |||
| GO:0030424 | ||||
| GO:0008021 | ||||
| Subcellular_localization | When expressed in cholinergic DA and DB motor neurons, NLG-1::GFP exhibited a punctate distribution in dorsal cord axons but was diffuse in ventral cord dendrites. Dorsal cord NLG-1 puncta co-localized with a synaptic vesicle (SV) marker (mCherry-tagged UNC-57 endophilin). NRX-1::GFP expressed in body muscles was also punctate in the nerve cords and these NRX-1 puncta were often closely apposed to pre-synaptic UNC-57 puncta. | |||
| Type | Reporter_gene | The transcriptional reporter for nlg-1 used 6.5kb of 5' flanking sequence. A 2.4kb myo-3 myosin promoter was used for expression in body muscles, a 3.2kb unc-17 VAChT promoter was used for expression in cholinergic neurons, and a 2.6kb unc-129 promoter was used for expression in DA and DB motor neurons. | ||
| Pattern | The nlg-1 promoter expressed GFP in cholinergic motor neurons but not in GABAergic neurons. | |||
| Reference | WBPaper00041363 | |||
| Transgene | WBTransgene00015243 |
