WormBase Tree Display for Expr_pattern: Expr11021
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| Expr11021 | Expression_of | Gene | WBGene00006755 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006755 | |||
| Expression_data | Anatomy_term | WBbt:0005735 | Certain | |
| GO_term | GO:0045202 | |||
| GO:0043025 | ||||
| GO:0043194 | ||||
| GO:0043679 | ||||
| Type | Antibody | |||
| Pattern | UNC-16 was broadly expressed throughout the nervous system. By imaging the well-isolated ALM neuron, it was observed that UNC-16 was equally concentrated in its cell soma and its initial segment. The UNC-16 signal dropped off rapidly after the initial segment, but was still sparsely distributed throughout the remaining process and was also sparsely distributed in the dorsal axons of motor neurons in a pattern that did not align with synaptic sites. The localization of native UNC-16 is thus consistent with a function in the axon initial segment; however, it is also present on sparsely distributed structures distal to the initial segment and thus may also function at other locations. Immunolocalization of native UNC-16 showed that it is present in the synaptic region of axons. | |||
| Picture | WBPicture0000013076 | |||
| Reference | WBPaper00041921 | |||
| Antibody_info | WBAntibody00002438 |
