WormBase Tree Display for Expr_pattern: Expr13247
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| Expr13247 | Expression_of | Gene | WBGene00006662 | ||
|---|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006662 | ||||
| Expression_data | Anatomy_term | WBbt:0005274 | Certain | ||
| WBbt:0005278 | Certain | ||||
| WBbt:0005334 | Certain | ||||
| WBbt:0005336 | Certain | ||||
| WBbt:0005339 | Certain | ||||
| WBbt:0005829 | Certain | ||||
| WBbt:0006751 | Partial | ||||
| Remark | Expressed in some head and tail neurons. | ||||
| WBbt:0006759 | Partial | ||||
| Remark | Expressed in some head and tail neurons. | ||||
| GO_term | GO:0043025 | ||||
| Type | Reporter_gene | ||||
| Pattern | The twk-7 promoter drives DsRed reporter expression in some head and tail neurons as well as in all A-, B-, and AS-type motor neurons of the ventral nerve cord. In addition, DsRed expression was seen in GFP negative neurons. According to their number and stereotypic position, these TWK-7-expressing cells were identified as the 13 ventral and 6 dorsal GABAergic D-type motor neurons of the ventral nerve cord. The cell-type-specific expression pattern of TWK-7 was confirmed in worms that express a C-terminal tagged TWK-7::mCherry fusion protein under the control of the twk-7 promoter. TWK-7::mCherry was localized along the ventral nerve cord and in punctated structures in the soma of motor neurons. Taken together, in accordance with the unraveled impact of TWK-7 on locomotor activity of C. elegans, TWK-7 is expressed in all types of motor neurons of the ventral nerve cord that control body-wall muscle activity. | ||||
| The twk-7 promoter drives DsRed reporter expression in some head and tail neurons as well as in all A-, B-, and AS-type motor neurons of the ventral nerve cord. In addition, DsRed expression was seen in GFP2 neurons. According to their number and stereotypic position, these TWK-7-expressing cells were identified as the 13 ventral and 6 dorsal GABAergic D-type motor neurons of the ventral nerve cord. The cell-type-specific expression pattern of TWK-7 was confirmed in worms that express a C-terminal tagged TWK-7::mCherry fusion protein under the control of the twk-7 promoter. TWK-7::mCherry was localized along the ventral nerve cord and in punctated structures in the soma of motor neurons. Taken together, in accordance with the unraveled impact of TWK-7 on locomotor activity of C. elegans, TWK-7 is expressed in all types of motor neurons of the ventral nerve cord that control body-wall muscle activity. | |||||
| Picture | WBPicture0000014366 | ||||
| WBPicture0000014367 | |||||
| Reference | WBPaper00049960 | ||||
| Transgene | WBTransgene00010210 |
