WormBase Tree Display for Expr_pattern: Expr1329
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| Expr1329 | Expression_of | Gene | WBGene00006778 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006778 | ||
| Expression_data | Life_stage | WBls:0000022 | |
| WBls:0000015 | |||
| WBls:0000014 | |||
| WBls:0000021 | |||
| Anatomy_term (40) | |||
| Type | Antibody | Polyclonal mice or rabbit antibody against UNC-42 recombinant protein. | |
| Reporter_gene | |||
| Pattern | UNC-42 expression was detected with a mouse antiserum in several cells as early as 260 minutes of embryogenesis and in neurons at high levels in the head by comma stage, the time when these neurons extend axons and establish connections. Expression in head neurons continues into adulthood. UNC-42 was strongly expressed in at least 20 pairs of neurons of the head, including the AVA, AVD and AVE interneurons, ASH sensory neurons, and RMD and SMB motor neurons. Other neurons that express high levels of UNC-42 include the AIN, AVH, AVJ, AVK, RIV, SAA and SIB interneurons. The same expression pattern in the head was detected in animals that carry a transgene that encodes an UNC-42 protein tagged at its C terminus with GFP(gmEx186). Antiserum to UNC-42 and the gmEx104 GFP reporter gene revealed low levels of unc-42 expression in hypodermis and additional neurons in the head. Transient expression of UNC-42 protein was also detected in the DD motor neurons at hatching and at low levels in postembryonic ventral cord motor neurons derived from P11. UNC-42 protein was not detected in descendants of P2-P10 or P12. In the tail, unc-42-gfp (gmEx104) is strongly expressed in PVT. | ||
| Picture | WBPicture0000008017 | ||
| Reference | WBPaper00003555 | ||
| Transgene | WBTransgene00027466 | ||
| Antibody_info | WBAntibody00000226 | ||
| WBAntibody00000227 |
