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WormBase Tree Display for Expr_pattern: Expr14682

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Name Class

Expr14682Expression_ofGeneWBGene00006793
Reflects_endogenous_expression_ofWBGene00006793
Expression_dataLife_stageWBls:0000003
WBls:0000038Anatomy_termWBbt:0005821
WBls:0000027Anatomy_termWBbt:0005175
WBbt:0006865
WBbt:0008373
WBls:0000035Anatomy_termWBbt:0005175
WBbt:0005821
WBbt:0006865
WBbt:0008373
WBls:0000041Anatomy_termWBbt:0005753
WBls:0000023Anatomy_termWBbt:0005753
WBls:0000007
WBls:0000008
Anatomy_term (15)
GO_termGO:0032154
TypeGenome_editing
Reporter_gene
PatternWe first show the localization of UNC-59 at the cleavage furrow (previously shown with antibody staining, (Nguyen et al. 2000)) during a time lapse of cell divisions in early 2- to 4-cell stages of embryogenesis and throughout embryogenesis (cleavage rings in older embryos. Septins are also important for gonad morphogenesis and distal tip cell (DTC) migration (Nguyen et al. 2000) where UNC-59 protein is detected throughout gonad development in the rachis (previously shown with endogenously tagged unc-59::mKate, (Priti et al. 2018)) and DTCs. We highlight UNC-59/Septin localization in the DTC (previously shown with a transgene, (Finger et al. 2003)) at the L2 and L3 stages where it is organized into bundles (DeMay et al. 2011) and ring structures. The two bilateral sex myoblast cells express UNC-59 during their posterior to anterior migration in the L2 and early L3 stage and continue to express UNC-59 in these cells as they differentiate into vulval muscles in the late L3 to early L4 stages. Lastly, we show UNC-59/Septin expression and localization in tissue not previously reported: in the pharynx (cells of the buccal cavity, anterior procorpus, and terminal bulb); in the seam cells, both in bundles and at the cleavage furrows, beginning in the L1 stage and continuing throughout development and into the adult; and in sperm surrounding an embryo that has exited the spermatheca.
PictureWBPicture0000014940
ReferenceWBPaper00058988
VariationWBVar02152777