WormBase Tree Display for Expr_pattern: Expr16132
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| Expr16132 | Expression_of | Gene | WBGene00003377 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00003377 | |||
| Expression_data | Life_stage | WBls:0000003 | Anatomy_term (11) | |
| Anatomy_term (11) | ||||
| Type | Reporter_gene | |||
| Pattern | GFP::MLS-2 expression became detectable around the 50-cell stage of embryogenesis and was restricted to specific, reproducible sublineages of the AB blastomere, most of which gave rise to neuronal and/or glial descendants. GFP::MLS-2 was also expressed in the duct and pore lineages, but was never observed in the canal cell. In 3/3 movies, we saw that expression of GFP::MLS-2 initiated in the grandparents of the duct and pore cell. GFP::MLS- 2 expression persisted in the duct and pore cells through the ventral enclosure and 1.5-fold stages of embryonic development, during which time fates are specified via EGF-Ras- ERK signaling and the duct and pore cells stack and form tubes (Abdus-Saboor et al., 2011). By the first larval stage of development, when the duct and pore cells have achieved their mature morphologies, GFP::MLS-2 was no longer detected in the duct and pore cells. | |||
| Reference | WBPaper00041013 | |||
| Transgene | WBTransgene00014961 |
