WormBase Tree Display for Expr_pattern: Expr1773

Expr1773 Expression_of: Gene: WBGene00002210
    Reflects_endogenous_expression_of: WBGene00002210
  Expression_data: Life_stage: WBls:0000024
      WBls:0000003
      WBls:0000038
      WBls:0000027
      WBls:0000035
      WBls:0000041
      WBls:0000032
    Anatomy_term (27)
    GO_term: GO:0005737
  Subcellular_localization: KIN-29::GFP was localized cytoplasmically, and was excluded from the nuclei of most, if not all, cell types. KIN-29::GFP was localized cytoplasmically at all stages of development examined, including in dauer larvae. However, KIN-29::GFP was rapidly translocated to the nucleus upon heat shock, but not upon starvation for 18 hr, addition of dauer pheromone, or in a tph-1 mutant background, although transient nuclear localization in a subset of cell types cannot be ruled out. Heat shock-induced translocation was observed in most, if not all cells, including neurons, muscles, and hypodermal cells. Translocation was reversible; KIN-29::GFP was relocalized to the cytoplasm within an hour upon temperature downshift.
  Type: Reporter_gene
  Pattern: kin-29::GFP expression was primarily neuronal, with additional expression in body wall muscle and hypodermal cells. Expression persisted through all stages of postembryonic development. Among neuronal cells, kin-29 was expressed in multiple sensory neurons and interneurons in the lateral, anterior, and lumbar ganglia, as well as in motor neurons in the ventral motor cord. kin-29::GFP colocalizes with odr-1::RFP expression in both the AWB and AWC olfactory neurons. kin-29 was also expressed in the ASH, AFD, ASJ, AWA, ASK, ASG, and ASI sensory neurons. In addition, kin-29 was expressed in the AIY and AIZ interneurons. Additional kin-29-expressing cells were not identified definitively.
  Picture: WBPicture0000009619
  Reference: WBPaper00005098
  Transgene: WBTransgene00027668