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WormBase Tree Display for Expr_pattern: Expr2746

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Name Class

Expr2746Expression_ofGeneWBGene00006819
Reflects_endogenous_expression_ofWBGene00006819
Expression_dataGO_termGO:0005884
Subcellular_localizationIn REF 52 fibroblasts UNC-87 localized to the actin stress fibers, and the ectopic expression of the UNC-87 protein caused a significant increase in stress fiber bundling. Moreover, stress fiber formation was significantly enhanced in the mouse melanoma cell line B16F1.
RemarkType: mammalian cell transfection. UNC-87 cDNA was cloned into the pEGFP C1 vector to generate a mutant protein fused to GFP at its amino terminus. Various cell lines were transfected with this construct, and the cellular localization was determined by fluorescence microscopy.
ReferenceWBPaper00004578