WormBase Tree Display for Expr_pattern: Expr3160
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| Expr3160 | Expression_of | Gene | WBGene00003136 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00003136 | ||
| Expression_data | Life_stage | WBls:0000024 | |
| WBls:0000003 | |||
| WBls:0000038 | |||
| WBls:0000027 | |||
| WBls:0000035 | |||
| WBls:0000041 | |||
| Type | Western | ||
| Pattern | Overall, the content of MAU-2 protein is similar through all developmental stages, including at times of cellular and axonal migrations. Upon repeated immunoblot analysis, there appeared to be a slight enrichment in the embryos and L1 larvae compared with other larval stages, which could reflect a higher need for MAU-2 during the time when numerous cellular migrations occur. | ||
| The level of MAU-2 was examined in the germline mutants glp-4(bn2ts), fem-3(q20ts) and fem-2(b245ts) compared with the wild type. The level of MAU-2 in germline mutants is similar to the wild type, indicating that MAU-2 is not particularly enriched in the germline. Thus, the maternal mau-2 product that is provided to the zygote via the oocyte appears to be principally RNA. Maternally contributed mau-2 mRNA is probably responsible for the maternal rescue effect observed with mau-2 mutations. | |||
| Reference | WBPaper00024594 |
