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WormBase Tree Display for Expr_pattern: Expr3750

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Name Class

Expr3750Expression_ofGeneWBGene00009882
Reflects_endogenous_expression_ofWBGene00009882
Expression_dataLife_stageWBls:0000024
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
WBls:0000018
WBls:0000019
WBls:0000020
WBls:0000017
WBls:0000021
Anatomy_term (14)
GO_termGO:0016324
GO:0043296
Subcellular_localizationAs the embryo develops, FUS-1 levels increase in these epidermal cells, where it concentrates almost exclusively on the apical membrane and some colocalizes with apical junctions.
TypeAntibody
PatternAnti-FUS-1 antibody first detects FUS-1 in a punctate pattern within the gut cells of embryos at approximately the comma stage (~6 hr pf); it is undetectable in epidermal cells at this early stage. FUS-1 is also detected in the excretory cell and the apical membrane of gut cells starting later in embryogenesis. In the epidermis, the protein is first conspicuously detected in 2-fold stage embryos shortly after most epidermal cell fusions occur. Initially, FUS-1 expression is seen at approximately equal levels throughout the dorsal, ventral, and anterior epidermal cells; it is specifically excluded from the lateral seam cells. FUS-1 remains virtually undetectable in seam cells, which neither fuse in wild-type embryos and fus-1 mutants nor express EFF-1.
PictureWBPicture0000009973
ReferenceWBPaper00026591
Antibody_infoWBAntibody00000847