WormBase Tree Display for Expr_pattern: Expr8869
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| Expr8869 | Expression_of | Gene | WBGene00011415 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00011415 | |||
| Expression_data | Anatomy_term | WBbt:0005784 | Certain | |
| GO_term | GO:0005694 | |||
| GO:0043073 | ||||
| Subcellular_localization | HIM-18 is first observed in mitotic nuclei at the distal tip region of the germline (premeiotic tip). However, the HIM-18 signal is abruptly reduced as nuclei enter into meiotic prophase, being barely visible in the transition zone (leptotene/zygotene) or in early to mid pachytene nuclei. HIM-18 signal is then clearly detected once again in late pachytene nuclei, persisting through the end of diakinesis. At a higher resolution, the HIM-18 signal is observed as nuclear foci (mainly around the chromosomes) in the premeiotic tip, late pachytene and diplotene/diakinesis stages. Although the HIM-18 signal is reduced from transition zone through mid-pachytene, a low level of HIM-18 foci, both on and around chromosomes, is still apparent at these stages upon longer exposure. Finally, HIM-18 is no longer observed localizing onto chromosomes after diakinesis. | |||
| Type | Antibody | |||
| Picture | WBPicture0000007424 | |||
| Remark | Picture: Figure 1C. | |||
| Reference | WBPaper00035505 | |||
| Antibody_info | WBAntibody00002070 |
