WormBase Tree Display for Gene: HGNC:9995
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| HGNC:9995 | Identity | Name | CGC_name | Rgs13 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:1604849 | |||||
| MGC17173 | ||||||
| regulator of G-protein signaling 13 | ||||||
| regulator of G-protein signalling 13 | ||||||
| Public_name | Rgs13 | |||||
| DB_info | Database | HGNC | id | 9995 | ||
| AGR | cURI | HGNC:9995 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000127074 | ||||
| UniProt | UniProt_AC | O14921 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00004350 | Caenorhabditis elegans | From_analysis | OrthoFinder | ||
| Panther | ||||||
| PhylomeDB | ||||||
| WBGene00004353 | Caenorhabditis elegans | From_analysis | OrthoFinder | |||
| Panther | ||||||
| PhylomeDB | ||||||
| Structured_description | Automated_description | The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008] | Inferred_automatically | AGR_import |
