WormBase Tree Display for Gene: WBGene00000053
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| WBGene00000053 | SMap | S_parent | Sequence | T05C12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | acr-14 | Person_evidence | WBPerson1430 | |||||
| Sequence_name | T05C12.2 | ||||||||
| Molecular_name | T05C12.2 | ||||||||
| T05C12.2.1 | |||||||||
| CE25099 | |||||||||
| Other_name | CELE_T05C12.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | acr-14 | ||||||||
| DB_info | Database | AceView | gene | 2I462 | |||||
| WormQTL | gene | WBGene00000053 | |||||||
| WormFlux | gene | WBGene00000053 | |||||||
| NDB | locus_tag | CELE_T05C12.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000053|UniProtKB=Q22224 | |||||||
| family | PTHR18945 | ||||||||
| NCBI | gene | 191601 | |||||||
| RefSeq | protein | NM_063315.3 | |||||||
| TrEMBL | UniProtAcc | Q22224 | |||||||
| UniProt_GCRP | UniProtAcc | Q22224 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:19 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | acr | ||||||||
| Allele (30) | |||||||||
| Strain | WBStrain00031836 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (28) | |||||||||
| Ortholog | WBGene00053805 | Caenorhabditis remanei | From_analysis | OMA | |||||
| TreeFam | |||||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00024072 | Caenorhabditis briggsae | From_analysis | Hillier-set | ||||||
| OrthoMCL | |||||||||
| OMA | |||||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00147758 | Caenorhabditis brenneri | From_analysis | OMA | ||||||
| TreeFam | |||||||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00190745 | Caenorhabditis brenneri | From_analysis | TreeFam | ||||||
| WormBase-Compara | |||||||||
| CBOVI.g6368 | Caenorhabditis bovis | From_analysis | WormBase-Compara | ||||||
| CSP21.g3130 | Caenorhabditis parvicauda | From_analysis | WormBase-Compara | ||||||
| CSP26.g6461 | Caenorhabditis zanzibari | From_analysis | WormBase-Compara | ||||||
| CSP28.g12817 | Caenorhabditis panamensis | From_analysis | WormBase-Compara | ||||||
| CSP29.g6427 | Caenorhabditis becei | From_analysis | WormBase-Compara | ||||||
| CSP31.g9410 | Caenorhabditis uteleia | From_analysis | WormBase-Compara | ||||||
| CSP32.g9450 | Caenorhabditis sulstoni | From_analysis | WormBase-Compara | ||||||
| CSP38.g2225 | Caenorhabditis quiockensis | From_analysis | WormBase-Compara | ||||||
| CSP39.g6632 | Caenorhabditis waitukubuli | From_analysis | WormBase-Compara | ||||||
| CSP40.g19260 | Caenorhabditis tribulationis | From_analysis | WormBase-Compara | ||||||
| CSP40.g19261 | Caenorhabditis tribulationis | From_analysis | WormBase-Compara | ||||||
| Cni-acr-14 | Caenorhabditis nigoni | From_analysis | WormBase-Compara | ||||||
| Csp11.Scaffold630.g18519 | Caenorhabditis tropicalis | From_analysis | WormBase-Compara | ||||||
| Csp11.Scaffold630.g21277 | Caenorhabditis tropicalis | From_analysis | WormBase-Compara | ||||||
| Csp5_scaffold_00451.g11547 | Caenorhabditis sinica | From_analysis | WormBase-Compara | ||||||
| FL83_08771 | Caenorhabditis latens | From_analysis | WormBase-Compara | ||||||
| GCK72_005080 | Caenorhabditis remanei | From_analysis | WormBase-Compara | ||||||
| OTIPU.nOt.2.0.1.g07670 | Oscheius tipulae | From_analysis | WormBase-Compara | ||||||
| Sp34_20154320 | Caenorhabditis inopinata | From_analysis | WormBase-Compara | ||||||
| chrII_pilon.g5179 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00183093 | Caenorhabditis japonica | From_analysis | WormBase-Compara | ||||||
| WBGene00114769 | Pristionchus pacificus | From_analysis | WormBase-Compara | ||||||
| FB:FBgn0086778 | Drosophila melanogaster | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| FB:FBgn0032151 | Drosophila melanogaster | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| FB:FBgn0028875 | Drosophila melanogaster | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| ZFIN:ZDB-GENE-040108-3 | Danio rerio | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| ZFIN:ZDB-GENE-060503-606 | Danio rerio | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| ZFIN:ZDB-GENE-090313-161 | Danio rerio | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| HGNC:1960 | Homo sapiens | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| HGNC:15781 | Homo sapiens | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| MGI:99779 | Mus musculus | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| RGD:2348 | Rattus norvegicus | From_analysis | OrthoFinder | ||||||
| Panther | |||||||||
| PhylomeDB | |||||||||
| Paralog (100) | |||||||||
| Structured_description | Concise_description | acr-14 encodes a protein that contains neurotransmitter-gated ion-channel ligand-binding and transmembrane domains. | Curator_confirmed | WBPerson48 | |||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in intestine; muscle cell; and neurons. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Lewy body dementia; carcinoma (multiple); and inflammatory bowel disease (multiple). Is an ortholog of human CHRFAM7A (CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion) and CHRNA7 (cholinergic receptor nicotinic alpha 7 subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||
| DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||||
| DOID:3748 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||||
| DOID:8778 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||||
| DOID:3083 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||||
| DOID:12217 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||||
| DOID:8577 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||||
| DOID:1324 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||||
| DOID:7474 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||||
| DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1960) | ||||||
| Molecular_info | Corresponding_CDS | T05C12.2 | |||||||
| Corresponding_transcript | T05C12.2.1 | ||||||||
| Other_sequence | JI180092.1 | ||||||||
| Associated_feature | WBsf223455 | ||||||||
| WBsf223456 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00066388 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00097922 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00052489 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00018218 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00078345 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035191 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1906 | ||||||||
| Expr4858 | |||||||||
| Expr8203 | |||||||||
| Expr10607 | |||||||||
| Expr13428 | |||||||||
| Expr1018728 | |||||||||
| Expr1156115 | |||||||||
| Expr2009181 | |||||||||
| Expr2027420 | |||||||||
| Drives_construct (11) | |||||||||
| Construct_product | WBCnstr00016680 | ||||||||
| WBCnstr00037766 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (91) | |||||||||
| Interaction (28) | |||||||||
| Map_info | Map | II | Position | 0.742235 | Error | 0.001179 | |||
| Positive | Positive_clone | T05C12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4965 | |||||||
| 4646 | |||||||||
| 5546 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (26) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
