WormBase Tree Display for Gene: WBGene00000065
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| WBGene00000065 | SMap | S_parent | Sequence | T04C12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | act-3 | Person_evidence | WBPerson259 | |||||
| Sequence_name | T04C12.4 | ||||||||
| Molecular_name | T04C12.4 | ||||||||
| T04C12.4.1 | |||||||||
| CE13148 | |||||||||
| T04C12.4.2 | |||||||||
| T04C12.4.3 | |||||||||
| Other_name | act1 | Accession_evidence | EMBL | X16796 | |||||
| act3 | Accession_evidence | EMBL | X16798 | ||||||
| CELE_T04C12.4 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | act-3 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | act | ||||||||
| Allele | WBVar00000059 | Inferred_automatically | From strain object: DA468 | ||||||
| WBVar00248704 | Inferred_automatically | From strain object: RW3455 | |||||||
| WBVar01499929 | |||||||||
| WBVar01865455 | |||||||||
| WBVar01865456 | |||||||||
| WBVar01484680 | |||||||||
| WBVar00469954 | |||||||||
| WBVar00469955 | |||||||||
| WBVar00469956 | |||||||||
| WBVar02141162 | |||||||||
| WBVar01274899 | |||||||||
| WBVar00469961 | |||||||||
| WBVar01046522 | |||||||||
| WBVar01046523 | |||||||||
| WBVar01046524 | |||||||||
| WBVar01046525 | |||||||||
| WBVar01046526 | |||||||||
| WBVar01046527 | |||||||||
| WBVar01046528 | |||||||||
| WBVar01046529 | |||||||||
| WBVar01046530 | |||||||||
| WBVar01046531 | |||||||||
| WBVar01046532 | |||||||||
| WBVar01046533 | |||||||||
| WBVar01499645 | |||||||||
| WBVar01046534 | |||||||||
| WBVar01499646 | |||||||||
| WBVar01046535 | |||||||||
| WBVar01743350 | |||||||||
| WBVar01743351 | |||||||||
| WBVar01046536 | |||||||||
| WBVar01046537 | |||||||||
| WBVar01046538 | |||||||||
| WBVar01046539 | |||||||||
| WBVar01461689 | |||||||||
| WBVar01500208 | |||||||||
| WBVar01500209 | |||||||||
| WBVar01499299 | |||||||||
| WBVar00003590 | |||||||||
| WBVar01499316 | |||||||||
| Strain | WBStrain00033516 | ||||||||
| WBStrain00005465 | |||||||||
| In_cluster | act-123 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| Ortholog (46) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Concise_description | act-3 encodes an invertebrate actin, highly similar to ACT-1, ACT-2, and ACT-4, that functions in body wall muscle; act-3 functions with two other action isoforms, act-1 and act-2, to control cytoplasmic microfilament function in the early embryo. | Paper_evidence | WBPaper00000741 | |||||
| WBPaper00001178 | |||||||||
| WBPaper00001709 | |||||||||
| WBPaper00014413 | |||||||||
| WBPaper00027028 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 29 Mar 2007 00:00:00 | ||||||||
| Automated_description | Expressed in gonad and head. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Human ACTB Contributes to nucleosomal DNA binding activity. Human ACTB enables several functions, including Tat protein binding activity; enzyme binding activity; and kinesin binding activity. A structural constituent of postsynaptic actin cytoskeleton. Is predicted to encode a protein with the following domains: ATPase, nucleotide binding domain; Phosphorylation site; Actin; and Actin family. Is an ortholog of human ACTB (actin beta). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1588 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||
| DOID:0081113 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:144) | ||||||
| DOID:10881 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||||
| DOID:0081112 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||||
| DOID:0110550 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:144) | ||||||
| Molecular_info | Corresponding_CDS | T04C12.4 | |||||||
| Corresponding_transcript | T04C12.4.1 | ||||||||
| T04C12.4.2 | |||||||||
| T04C12.4.3 | |||||||||
| Other_sequence (48) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result (47) | ||||||||
| Expr_pattern | Chronogram981 | ||||||||
| Expr4555 | |||||||||
| Expr6598 | |||||||||
| Expr14934 | |||||||||
| Expr1030026 | |||||||||
| Expr1155998 | |||||||||
| Expr2009223 | |||||||||
| Expr2027460 | |||||||||
| Drives_construct | WBCnstr00002476 | ||||||||
| WBCnstr00037758 | |||||||||
| WBCnstr00041591 | |||||||||
| Construct_product | WBCnstr00037758 | ||||||||
| Antibody | WBAntibody00001783 | ||||||||
| Microarray_results (48) | |||||||||
| Expression_cluster (167) | |||||||||
| Interaction (298) | |||||||||
| Map_info | Map | V | Position | 2.92811 | Error | 0.004379 | |||
| Positive | Positive_clone | T04C12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4140 | |||||||
| 4141 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (63) | |||||||||
| Remark | M03F4.2 connection removed since latter is on another chromosome. [sdm 0107] | ||||||||
| T04C12.6 connection removed. email from JAH 0109. | |||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
