WormBase Tree Display for Gene: WBGene00000065

WBGene00000065 SMap: S_parent: Sequence: T04C12
  Identity: Version: 1
    Name: CGC_name: act-3 Person_evidence: WBPerson259
      Sequence_name: T04C12.4
      Molecular_name: T04C12.4
        T04C12.4.1
        CE13148
        T04C12.4.2
        T04C12.4.3
      Other_name: act1 Accession_evidence: EMBL X16796
        act3 Accession_evidence: EMBL X16798
        CELE_T04C12.4 Accession_evidence: NDB BX284605
      Public_name: act-3
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: act
    Allele (40)
    Strain: WBStrain00033516
      WBStrain00005465
    In_cluster: act-123
    RNASeq_FPKM (74)
    Ortholog: WBGene00025260 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00025261 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00025265 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00025266 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00037707 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00041507 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
      WBGene00041508 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00042553 Caenorhabditis briggsae From_analysis: OrthoMCL
      WBGene00066197 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            WormBase-Compara
      WBGene00051763 Caenorhabditis remanei From_analysis: OMA
      WBGene00085263 Caenorhabditis remanei From_analysis: OMA
      WBGene00066199 Caenorhabditis remanei From_analysis: OMA
      WBGene00098673 Pristionchus pacificus From_analysis: OMA
            WormBase-Compara
      WBGene00225347 Brugia malayi From_analysis: WormBase-Compara
      WBGene00228785 Brugia malayi From_analysis: WormBase-Compara
      WBGene00229498 Brugia malayi From_analysis: WormBase-Compara
      WBGene00229499 Brugia malayi From_analysis: WormBase-Compara
      CSP21.g3544 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP31.g1121 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP38.g15217 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      GCK72_016607 Caenorhabditis remanei From_analysis: WormBase-Compara
      chrV_pilon.g15679 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00239553 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00239554 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00272225 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00276137 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00258064 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00261913 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00264369 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00288575 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000001855 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0000042 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      FB:FBgn0000043 Drosophila melanogaster From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      FB:FBgn0000044 Drosophila melanogaster From_analysis: Hieranoid
            OrthoFinder
            Panther
      FB:FBgn0000045 Drosophila melanogaster From_analysis: Hieranoid
            OrthoFinder
            Panther
      FB:FBgn0000047 Drosophila melanogaster From_analysis: Hieranoid
            OrthoFinder
            Panther
      FB:FBgn0000046 Drosophila melanogaster From_analysis: Hieranoid
            OrthoFinder
            Panther
      ZFIN:ZDB-GENE-000329-1 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-000329-3 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:132 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:144 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      MGI:87904 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:87906 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      RGD:628837 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1304556 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
      RGD:2320108 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            SonicParanoid
    Paralog (11)
    Structured_description: Concise_description: act-3 encodes an invertebrate actin, highly similar to ACT-1, ACT-2, and ACT-4, that functions in body wall muscle; act-3 functions with two other action isoforms, act-1 and act-2, to control cytoplasmic microfilament function in the early embryo. Paper_evidence: WBPaper00000741
            WBPaper00001178
            WBPaper00001709
            WBPaper00014413
            WBPaper00027028
          Curator_confirmed: WBPerson324
            WBPerson567
          Date_last_updated: 29 Mar 2007 00:00:00
      Automated_description: Expressed in gonad and head. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Human ACTB Contributes to nucleosomal DNA binding activity. Human ACTB enables several functions, including Tat protein binding activity; enzyme binding activity; and kinesin binding activity. A structural constituent of postsynaptic actin cytoskeleton. Is predicted to encode a protein with the following domains: ATPase, nucleotide binding domain; Phosphorylation site; Actin; and Actin family. Is an ortholog of human ACTB (actin beta). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:1588 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:132)
      DOID:0081113 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:144)
      DOID:10881 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:132)
      DOID:0081112 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:132)
      DOID:0110550 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:144)
  Molecular_info: Corresponding_CDS: T04C12.4
    Corresponding_transcript: T04C12.4.1
      T04C12.4.2
      T04C12.4.3
    Other_sequence (48)
    Associated_feature (11)
  Experimental_info: RNAi_result (47)
    Expr_pattern: Chronogram981
      Expr4555
      Expr6598
      Expr14934
      Expr1030026
      Expr1155998
      Expr2009223
      Expr2027460
    Drives_construct: WBCnstr00002476
      WBCnstr00037758
      WBCnstr00041591
    Construct_product: WBCnstr00037758
    Antibody: WBAntibody00001783
    Microarray_results (48)
    Expression_cluster (167)
    Interaction (298)
  Map_info: Map: V Position: 2.92811 Error: 0.004379
    Positive: Positive_clone: T04C12 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4140
        4141
    Pseudo_map_position
  Reference (63)
  Remark: M03F4.2 connection removed since latter is on another chromosome. [sdm 0107]
    T04C12.6 connection removed. email from JAH 0109.
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene