WormBase Tree Display for Gene: WBGene00000065
expand all nodes | collapse all nodes | view schema
WBGene00000065 | SMap | S_parent | Sequence | T04C12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | act-3 | Person_evidence | WBPerson259 | |||||
Sequence_name | T04C12.4 | ||||||||
Molecular_name | T04C12.4 | ||||||||
T04C12.4.1 | |||||||||
CE13148 | |||||||||
T04C12.4.2 | |||||||||
T04C12.4.3 | |||||||||
Other_name | act1 | Accession_evidence | EMBL | X16796 | |||||
act3 | Accession_evidence | EMBL | X16798 | ||||||
CELE_T04C12.4 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | act-3 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | act | ||||||||
Allele (40) | |||||||||
Strain | WBStrain00033516 | ||||||||
WBStrain00005465 | |||||||||
In_cluster | act-123 | ||||||||
RNASeq_FPKM (74) | |||||||||
Ortholog (46) | |||||||||
Paralog (11) | |||||||||
Structured_description | Concise_description | act-3 encodes an invertebrate actin, highly similar to ACT-1, ACT-2, and ACT-4, that functions in body wall muscle; act-3 functions with two other action isoforms, act-1 and act-2, to control cytoplasmic microfilament function in the early embryo. | Paper_evidence | WBPaper00000741 | |||||
WBPaper00001178 | |||||||||
WBPaper00001709 | |||||||||
WBPaper00014413 | |||||||||
WBPaper00027028 | |||||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 29 Mar 2007 00:00:00 | ||||||||
Automated_description | Expressed in gonad and head. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Human ACTB Contributes to nucleosomal DNA binding activity. Human ACTB enables several functions, including Tat protein binding activity; enzyme binding activity; and kinesin binding activity. A structural constituent of postsynaptic actin cytoskeleton. Is predicted to encode a protein with the following domains: ATPase, nucleotide binding domain; Phosphorylation site; Actin; and Actin family. Is an ortholog of human ACTB (actin beta). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:1588 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||
DOID:0081113 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:144) | ||||||
DOID:10881 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||||
DOID:0081112 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||||
DOID:0110550 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:144) | ||||||
Molecular_info | Corresponding_CDS | T04C12.4 | |||||||
Corresponding_transcript | T04C12.4.1 | ||||||||
T04C12.4.2 | |||||||||
T04C12.4.3 | |||||||||
Other_sequence (48) | |||||||||
Associated_feature (11) | |||||||||
Experimental_info | RNAi_result (47) | ||||||||
Expr_pattern | Chronogram981 | ||||||||
Expr4555 | |||||||||
Expr6598 | |||||||||
Expr14934 | |||||||||
Expr1030026 | |||||||||
Expr1155998 | |||||||||
Expr2009223 | |||||||||
Expr2027460 | |||||||||
Drives_construct | WBCnstr00002476 | ||||||||
WBCnstr00037758 | |||||||||
WBCnstr00041591 | |||||||||
Construct_product | WBCnstr00037758 | ||||||||
Antibody | WBAntibody00001783 | ||||||||
Microarray_results (48) | |||||||||
Expression_cluster (167) | |||||||||
Interaction (298) | |||||||||
Map_info (4) | |||||||||
Reference (63) | |||||||||
Remark | M03F4.2 connection removed since latter is on another chromosome. [sdm 0107] | ||||||||
T04C12.6 connection removed. email from JAH 0109. | |||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |