WormBase Tree Display for Gene: WBGene00000231
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| WBGene00000231 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | D2045 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | atx-2 | |||||||
| Sequence_name | D2045.1 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_D2045.1 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | atx-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | atx | ||||||||
| Allele (108) | |||||||||
| Strain | WBStrain00007402 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (78) | |||||||||
| Ortholog (35) | |||||||||
| Structured_description | Concise_description | atx-2 is required for early embryonic patterning; it encodes an ortholog of human ataxin-2. | Paper_evidence | WBPaper00004103 | |||||
| WBPaper00004612 | |||||||||
| WBPaper00005068 | |||||||||
| WBPaper00012788 | |||||||||
| WBPaper00012830 | |||||||||
| WBPaper00012882 | |||||||||
| WBPaper00012897 | |||||||||
| WBPaper00013003 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable mRNA binding activity. Involved in several processes, including gamete generation; positive regulation of reproductive process; and regulation of cell cycle. Located in cytoplasm. Expressed in body wall musculature; dorsal nerve cord; germ line; gonad; and ventral nerve cord. Used to study autosomal dominant cerebellar ataxia. Human ortholog(s) of this gene implicated in late onset Parkinson's disease and spinocerebellar ataxia type 2. Is an ortholog of human ATXN2 (ataxin 2) and ATXN2L (ataxin 2 like). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:1441 | Homo sapiens | Paper_evidence | WBPaper00024364 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 02 Aug 2013 00:00:00 | ||||||||
| Potential_model | DOID:0050955 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10555) | |||||
| DOID:0060892 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10555) | ||||||
| Disease_relevance | Human Ataxin2 (ATXN2) contains a polygutamine tract, long expansions of which cause spinocerebellar ataxia-2. | Homo sapiens | Paper_evidence | WBPaper00024364 | |||||
| Accession_evidence | OMIM | 183090 | |||||||
| 601517 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 02 Aug 2013 00:00:00 | ||||||||
| Models_disease_in_annotation | WBDOannot00000221 | ||||||||
| Molecular_info | Corresponding_CDS | D2045.1a | |||||||
| D2045.1b | |||||||||
| D2045.1c | |||||||||
| D2045.1d | |||||||||
| Corresponding_CDS_history | D2045.1:wp132 | ||||||||
| D2045.1:wp138 | |||||||||
| D2045.1a:wp275 | |||||||||
| D2045.1b:wp275 | |||||||||
| D2045.1c:wp275 | |||||||||
| D2045.1d:wp275 | |||||||||
| Corresponding_transcript | D2045.1a.1 | ||||||||
| D2045.1b.1 | |||||||||
| D2045.1c.1 | |||||||||
| D2045.1d.1 | |||||||||
| Other_sequence (12) | |||||||||
| Associated_feature (16) | |||||||||
| Experimental_info | RNAi_result (46) | ||||||||
| Expr_pattern (12) | |||||||||
| Drives_construct | WBCnstr00000337 | ||||||||
| WBCnstr00013308 | |||||||||
| WBCnstr00037643 | |||||||||
| WBCnstr00039983 | |||||||||
| Construct_product | WBCnstr00037643 | ||||||||
| WBCnstr00039241 | |||||||||
| WBCnstr00039983 | |||||||||
| Antibody | WBAntibody00000787 | ||||||||
| WBAntibody00000788 | |||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (120) | |||||||||
| Interaction (198) | |||||||||
| Map_info | Map | III | Position | 2.51032 | Error | 0.003566 | |||
| Positive | Positive_clone | D2045 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference (44) | |||||||||
| Remark | Sequence connection from [Kiehl TR] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
