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WormBase Tree Display for Gene: WBGene00000478

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Name Class

WBGene00000478SMapS_parentSequenceF27E11
IdentityVersion1
NameCGC_namecfz-2Person_evidenceWBPerson194
Sequence_nameF27E11.3
Molecular_nameF27E11.3
F27E11.3.1
CE39149
Other_nameCELE_F27E11.3Accession_evidenceNDBBX284605
Public_namecfz-2
DB_infoDatabaseAceViewgene5D920
WormQTLgeneWBGene00000478
SignaLinkproteinWBGene00000478
WormFluxgeneWBGene00000478
NDBlocus_tagCELE_F27E11.3
PanthergeneCAEEL|EnsemblGenome=WBGene00000478|UniProtKB=G5ECQ2
familyPTHR11309
NCBIgene178768
RefSeqproteinNM_071564.8
SwissProtUniProtAccG5ECQ2
UniProt_GCRPUniProtAccG5ECQ2
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcfz
Allele (196)
StrainWBStrain00031864
WBStrain00008500
WBStrain00008502
WBStrain00008506
RNASeq_FPKM (74)
GO_annotation (29)
Ortholog (61)
ParalogWBGene00003006Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003238Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00003397Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00022242Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptioncfz-2 encodes one of four C. elegans Frizzled homologs, integral membrane proteins that contain an external cysteine-rich domain (CRD) and seven transmembrane domains and that function in a wide variety of species as receptors for Wnt glycoprotein signaling molecules; CFZ-2 activity is required for cell migration and for vulval development.Paper_evidenceWBPaper00026706
WBPaper00028436
WBPaper00032017
WBPaper00035405
WBPaper00037046
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated28 Oct 2010 00:00:00
Automated_descriptionPredicted to enable Wnt receptor activity and Wnt-protein binding activity. Involved in neuroblast migration; neuron migration; and positive regulation of motor neuron migration. Predicted to be located in plasma membrane. Expressed in intestine; nervous system; and pharynx. Is an ortholog of human FZD5 (frizzled class receptor 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF27E11.3
Corresponding_CDS_historyF27E11.3a:wp149
F27E11.3a:wp246
F27E11.3b:wp149
F27E11.3b:wp246
Corresponding_transcriptF27E11.3.1
Other_sequence (12)
Associated_feature (22)
Experimental_infoRNAi_resultWBRNAi00061144Inferred_automaticallyRNAi_primary
WBRNAi00045754Inferred_automaticallyRNAi_primary
WBRNAi00091577Inferred_automaticallyRNAi_primary
WBRNAi00045753Inferred_automaticallyRNAi_primary
WBRNAi00028248Inferred_automaticallyRNAi_primary
WBRNAi00014004Inferred_automaticallyRNAi_primary
WBRNAi00101351Inferred_automaticallyRNAi_primary
WBRNAi00098912Inferred_automaticallyRNAi_primary
Expr_patternExpr3645
Expr4446
Expr11482
Expr13819
Expr1026605
Expr1030280
Expr1149663
Expr2009941
Expr2028181
Drives_constructWBCnstr00011569
WBCnstr00012010
WBCnstr00040137
Construct_productWBCnstr00008352
WBCnstr00019046
Microarray_results (27)
Expression_cluster (208)
Interaction (46)
Anatomy_functionWBbtf0068
WBbtf0811
WBProcessWBbiopr:00000023
WBbiopr:00000073
Map_infoMapVPosition-11.6718Error0.034406
PositivePositive_cloneF27E11Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4881
4924
Pseudo_map_position
Reference (38)
RemarkSequence connection from [Endres JB, Cordes S, Hawkins N, Garriga G], [020802 krb]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene