WormBase Tree Display for Gene: WBGene00000512
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| WBGene00000512 | Evidence | Paper_evidence | WBPaper00005916 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | B0285 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | ckb-2 | |||||||
| Sequence_name | B0285.9 | ||||||||
| Molecular_name | B0285.9 | ||||||||
| B0285.9.1 | |||||||||
| CE33591 | |||||||||
| Other_name | CELE_B0285.9 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | ckb-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ckb | ||||||||
| Allele (28) | |||||||||
| Strain | WBStrain00003139 | ||||||||
| WBStrain00002768 | |||||||||
| WBStrain00032273 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Contained_in_operon | CEOP3176 | ||||||||
| Ortholog (60) | |||||||||
| Paralog | WBGene00000509 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000510 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000511 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000515 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00000513 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000514 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | ckb-2 encodes an isoform of choline kinase whose activity has beenverified in vitro; CKB-1 through CKB-4 comprise a related group ('B') ofcholine kinases; purified CKB-2 has a strong preference for choline overethanolamine, a specific activity of 2.4 micromol/min/mg protein and a pHoptimum near 10. | Paper_evidence | WBPaper00005916 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 11 Aug 2006 00:00:00 | ||||||||
| Automated_description | Enables choline kinase activity. Involved in CDP-choline pathway and IRE1-mediated unfolded protein response. Predicted to be located in cytoplasm. Expressed in head and tail. Human ortholog(s) of this gene implicated in several diseases, including colon adenoma; megaconial type congenital muscular dystrophy; narcolepsy; and recurrent hypersomnia. Is an ortholog of human CHKA (choline kinase alpha) and CHKB (choline kinase beta). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:8619 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1938) | ||||
| DOID:8986 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1938) | ||||||
| DOID:0050912 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1937) | ||||||
| DOID:9884 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1938) | ||||||
| DOID:0110632 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1938) | ||||||
| DOID:1059 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1938) | ||||||
| Molecular_info | Corresponding_CDS | B0285.9 | |||||||
| Corresponding_transcript | B0285.9.1 | ||||||||
| Other_sequence | CJC13898_1 | ||||||||
| Associated_feature | WBsf034276 | ||||||||
| WBsf645086 | |||||||||
| WBsf658823 | |||||||||
| WBsf658824 | |||||||||
| WBsf992104 | |||||||||
| WBsf1014742 | |||||||||
| WBsf224723 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr5041 | ||||||||
| Expr5042 | |||||||||
| Expr11241 | |||||||||
| Expr1025891 | |||||||||
| Expr1143067 | |||||||||
| Expr2010027 | |||||||||
| Expr2028268 | |||||||||
| Drives_construct | WBCnstr00003295 | ||||||||
| WBCnstr00004570 | |||||||||
| WBCnstr00037486 | |||||||||
| Construct_product | WBCnstr00037486 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (249) | |||||||||
| Interaction (223) | |||||||||
| Map_info | Map | III | Position | -3.18008 | Error | 0.000558 | |||
| Positive | Positive_clone | B0285 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005432 | ||||||||
| WBPaper00005916 | |||||||||
| WBPaper00031857 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00039975 | |||||||||
| WBPaper00042257 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062289 | |||||||||
| WBPaper00063813 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
