WormBase Tree Display for Gene: WBGene00000793
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WBGene00000793 | Evidence | Accession_evidence | EMBL | AB081595 | |||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | Y41C4A | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | crh | ||||||
Allele (986) | |||||||
Strain | WBStrain00040751 | ||||||
WBStrain00035398 | |||||||
WBStrain00055558 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (18) | |||||||
Ortholog (45) | |||||||
Paralog | WBGene00000222 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00002783 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00016162 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | crh-1 encodes a homolog of the cyclic AMP-response element binding protein (CREB); crh-1 is involved in the transcription of CRE-sequence dependant genes activated by a CaM kinase cascade; crh-1 is required in the bilateral thermosensory neuron AFD, for a memory-related behaviour and for response to tap (nonlocalized mechanosensory stimulation) and tap habituation; crh-1 appears to be ubiquitously expressed. | Paper_evidence | WBPaper00005563 | |||
WBPaper00029055 | |||||||
WBPaper00039855 | |||||||
WBPaper00039821 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson324 | |||||||
Date_last_updated | 02 Dec 2013 00:00:00 | ||||||
Automated_description | Enables identical protein binding activity and transcription coactivator binding activity. Involved in determination of adult lifespan; intracellular signal transduction; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in several structures, including germ line; gonad; head ganglion; intestine; and neurons. Human ortholog(s) of this gene implicated in Pick's disease and schizophrenia. Is an ortholog of human ATF1 (activating transcription factor 1); CREB1 (cAMP responsive element binding protein 1); and CREM (cAMP responsive element modulator). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:9976 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2345) | ||
DOID:0050741 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2345) | ||||
DOID:11870 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2345) | ||||
DOID:9975 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2345) | ||||
DOID:5419 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2345) | ||||
Molecular_info | Corresponding_CDS | Y41C4A.4a | |||||
Y41C4A.4b | |||||||
Y41C4A.4c | |||||||
Y41C4A.4d | |||||||
Y41C4A.4e | |||||||
Y41C4A.4f | |||||||
Y41C4A.4g | |||||||
Corresponding_CDS_history | Y41C4A.4a:wp89 | ||||||
Y41C4A.4b:wp89 | |||||||
Y41C4A.4c:wp89 | |||||||
Corresponding_transcript | Y41C4A.4a.1 | ||||||
Y41C4A.4b.1 | |||||||
Y41C4A.4c.1 | |||||||
Y41C4A.4d.1 | |||||||
Y41C4A.4e.1 | |||||||
Y41C4A.4f.1 | |||||||
Y41C4A.4g.1 | |||||||
Other_sequence (69) | |||||||
Associated_feature (43) | |||||||
Transcription_factor | WBTranscriptionFactor000257 | ||||||
Experimental_info | RNAi_result | WBRNAi00056358 | Inferred_automatically | RNAi_primary | |||
WBRNAi00095782 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00036995 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00006490 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00116042 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00115794 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00056360 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00087890 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00006495 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (12) | |||||||
Drives_construct | WBCnstr00008257 | ||||||
WBCnstr00012859 | |||||||
WBCnstr00038398 | |||||||
WBCnstr00038399 | |||||||
WBCnstr00041558 | |||||||
Construct_product (13) | |||||||
Regulate_expr_cluster | WBPaper00038172:crh-1null_down_regulated | ||||||
WBPaper00038172:crh-1null_up_regulated | |||||||
WBPaper00059816:crh-1(n3315)_downrgulated | |||||||
WBPaper00059816:crh-1(n3315)_uprgulated | |||||||
WBPaper00062440:crh-1(n3315)_downregulated | |||||||
WBPaper00062440:crh-1(n3315)_upregulated | |||||||
WBPaper00062440:crh-1(syb385)_downregulated | |||||||
WBPaper00062440:crh-1(syb385)_upregulated | |||||||
Antibody | WBAntibody00001853 | ||||||
Microarray_results (61) | |||||||
Expression_cluster (111) | |||||||
Interaction (63) | |||||||
WBProcess | WBbiopr:00000121 | ||||||
Map_info | Map | III | Position | 11.752 | Error | 0.036866 | |
Positive | Positive_clone | Y41C4A | Inferred_automatically | From CDS info | |||
From sequence, transcript, pseudogene data | |||||||
Mapping_data | Multi_point | 4239 | |||||
4497 | |||||||
Pseudo_map_position | |||||||
Reference (94) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |