WormBase Tree Display for Gene: WBGene00000901

WBGene00000901 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: W01G7
  Identity: Version: 1
    Name: CGC_name: daf-5 Person_evidence: WBPerson521
      Sequence_name: W01G7.1
      Molecular_name: W01G7.1
        W01G7.1.1
        CE18985
        W01G7.1.2
      Other_name: CELE_W01G7.1 Accession_evidence: NDB BX284602
      Public_name: daf-5
    DB_info: Database: AceView gene 2O324
        WormQTL gene WBGene00000901
        SignaLink protein WBGene00000901
        WormFlux gene WBGene00000901
        NDB locus_tag CELE_W01G7.1
        Panther gene CAEEL|WormBase=WBGene00000901|UniProtKB=G5EDM7
          family PTHR10005
        NCBI gene 175054
        RefSeq protein NM_064540.7
        SwissProt UniProtAcc G5EDM7
        UniProt_GCRP UniProtAcc G5EDM7
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: daf
    Reference_allele: WBVar00143963
    Allele (641)
    Legacy_information: e1386 : defective dauer formation (daf-2 suppressible). ES1 ME3. NA11.
      See also e1385, e1386
      [C.elegansII] e1386 : defective dauer formation. ES1 ME3. OA11: e1385 etc. [Riddle et al. 1991; Thomas et al. 1993; DR]
    Strain: WBStrain00026946
      WBStrain00030737
      WBStrain00004317
    RNASeq_FPKM (74)
    GO_annotation (20)
    Ortholog (28)
    Structured_description: Concise_description: daf-5 is an ortholog of human SKOR1 (SKI family transcriptional corepressor 1) and SKOR2 (SKI family transcriptional corepressor 2); daf-5 is involved in dauer entry, determination of adult lifespan, lipid storage, negative regulation of transcription from RNA polymerase II promoter, positive regulation of dauer larval development and transforming growth factor beta receptor signaling pathway; daf-5 is predicted to have SMAD binding activity, based on protein domain information; daf-5 is expressed in the muscle cell, gon_herm_dtc_P, gon_herm_dtc_A, certain interneurons, ganglion, hypodermis, intestine, and the head neurons; daf-5 is localized to the cytoplasm and the nucleus. Paper_evidence (18)
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 10 Apr 2017 00:00:00
      Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. Expressed in several structures, including XXX cell; ganglia; hermaphrodite distal tip cell; intestine; and muscle cell. Is an ortholog of human SKI (SKI proto-oncogene) and SKIL (SKI like proto-oncogene). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: W01G7.1
    Corresponding_transcript: W01G7.1.1
      W01G7.1.2
    Other_sequence: LSC01469_1
      CD203263.1
      CR09984
      CRC12262_1
    Associated_feature (24)
  Experimental_info: RNAi_result (17)
    Expr_pattern: Expr2861
      Expr2880
      Expr2881
      Expr1028726
      Expr1030565
      Expr1158077
      Expr2010780
      Expr2029017
    Drives_construct: WBCnstr00000991
      WBCnstr00000992
      WBCnstr00011005
      WBCnstr00011006
      WBCnstr00037209
    Construct_product: WBCnstr00011005
      WBCnstr00037209
    Microarray_results (20)
    Expression_cluster (134)
    Interaction: WBInteraction000000101
      WBInteraction000000106
      WBInteraction000000107
      WBInteraction000000108
      WBInteraction000000109
      WBInteraction000000171
      WBInteraction000000180
      WBInteraction000000181
      WBInteraction000000182
      WBInteraction000000183
      WBInteraction000000184
      WBInteraction000000185
      WBInteraction000000239
      WBInteraction000000302
      WBInteraction000000303
      WBInteraction000000304
      WBInteraction000000305
      WBInteraction000000306
      WBInteraction000000401
      WBInteraction000000402
      WBInteraction000000403
      WBInteraction000000442
      WBInteraction000000443
      WBInteraction000000444
      WBInteraction000000445
      WBInteraction000000475
      WBInteraction000000783
      WBInteraction000000868
      WBInteraction000001050
      WBInteraction000001148
      WBInteraction000001149
      WBInteraction000001150
      WBInteraction000001196
      WBInteraction000001197
      WBInteraction000001198
      WBInteraction000001199
      WBInteraction000001200
      WBInteraction000001216
      WBInteraction000001217
      WBInteraction000001218
      WBInteraction000001219
      WBInteraction000001220
      WBInteraction000001472
      WBInteraction000001572
      WBInteraction000002009
      WBInteraction000002259
      WBInteraction000002307
      WBInteraction000002308
      WBInteraction000002334
      WBInteraction000002335
      WBInteraction000002398
      WBInteraction000002630
      WBInteraction000002692
      WBInteraction000002693
      WBInteraction000002694
      WBInteraction000002970
      WBInteraction000002971
      WBInteraction000002981
      WBInteraction000004688
      WBInteraction000004689
      WBInteraction000004690
      WBInteraction000004691
      WBInteraction000004692
      WBInteraction000004693
      WBInteraction000004694
      WBInteraction000004695
      WBInteraction000004696
      WBInteraction000008698
      WBInteraction000008699
      WBInteraction000008700
      WBInteraction000008701
      WBInteraction000008702
      WBInteraction000008745
      WBInteraction000028842
      WBInteraction000029223
      WBInteraction000029478
      WBInteraction000029481
      WBInteraction000029483
      WBInteraction000029484
      WBInteraction000029485
      WBInteraction000029691
      WBInteraction000029827
      WBInteraction000029828
      WBInteraction000029829
      WBInteraction000029830
      WBInteraction000029831
      WBInteraction000030245
      WBInteraction000051060
      WBInteraction000051106
      WBInteraction000051122
      WBInteraction000051123
      WBInteraction000051124
      WBInteraction000051125
      WBInteraction000051126
      WBInteraction000051127
      WBInteraction000051128
      WBInteraction000051129
      WBInteraction000051130
      WBInteraction000051131
      WBInteraction000051132
      WBInteraction000051133
      WBInteraction000051134
      WBInteraction000051135
      WBInteraction000051136
      WBInteraction000051137
      WBInteraction000051138
      WBInteraction000051139
      WBInteraction000051140
      WBInteraction000051141
      WBInteraction000051142
      WBInteraction000051143
      WBInteraction000051144
      WBInteraction000051145
      WBInteraction000051146
      WBInteraction000051147
      WBInteraction000051148
      WBInteraction000051149
      WBInteraction000051150
      WBInteraction000051151
      WBInteraction000051153
      WBInteraction000051154
      WBInteraction000051155
      WBInteraction000051156
      WBInteraction000051157
      WBInteraction000051158
      WBInteraction000051159
      WBInteraction000051160
      WBInteraction000051161
      WBInteraction000051162
      WBInteraction000051163
      WBInteraction000051164
      WBInteraction000051165
      WBInteraction000051166
      WBInteraction000051167
      WBInteraction000051198
      WBInteraction000051244
      WBInteraction000051290
      WBInteraction000051336
      WBInteraction000052358
      WBInteraction000052366
      WBInteraction000052368
      WBInteraction000052445
      WBInteraction000052448
      WBInteraction000052450
      WBInteraction000052452
      WBInteraction000052454
      WBInteraction000052456
      WBInteraction000052758
      WBInteraction000052782
      WBInteraction000126438
      WBInteraction000126543
      WBInteraction000126685
      WBInteraction000126882
      WBInteraction000127002
      WBInteraction000127245
      WBInteraction000127512
      WBInteraction000138056
      WBInteraction000143147
      WBInteraction000165608
      WBInteraction000165609
      WBInteraction000165631
      WBInteraction000165664
      WBInteraction000165718
      WBInteraction000165904
      WBInteraction000166154
      WBInteraction000166517
      WBInteraction000174874
      WBInteraction000180411
      WBInteraction000197153
      WBInteraction000209368
      WBInteraction000224295
      WBInteraction000241327
      WBInteraction000254056
      WBInteraction000261764
      WBInteraction000267338
      WBInteraction000268636
      WBInteraction000271011
      WBInteraction000276150
      WBInteraction000292694
      WBInteraction000300928
      WBInteraction000302604
      WBInteraction000305499
      WBInteraction000316284
      WBInteraction000323351
      WBInteraction000334245
      WBInteraction000334281
      WBInteraction000338806
      WBInteraction000341935
      WBInteraction000349221
      WBInteraction000350493
      WBInteraction000351203
      WBInteraction000354912
      WBInteraction000358868
      WBInteraction000362833
      WBInteraction000367108
      WBInteraction000371478
      WBInteraction000373702
      WBInteraction000382071
      WBInteraction000390781
      WBInteraction000395086
      WBInteraction000396454
      WBInteraction000402202
      WBInteraction000402250
      WBInteraction000404043
      WBInteraction000404163
      WBInteraction000404360
      WBInteraction000408386
      WBInteraction000410719
      WBInteraction000414991
      WBInteraction000424213
      WBInteraction000430617
      WBInteraction000431286
      WBInteraction000434675
      WBInteraction000436062
      WBInteraction000452449
      WBInteraction000517974
      WBInteraction000517975
      WBInteraction000518711
      WBInteraction000520184
      WBInteraction000522105
      WBInteraction000522132
      WBInteraction000522153
      WBInteraction000536043
      WBInteraction000536045
      WBInteraction000536047
      WBInteraction000536049
      WBInteraction000536051
      WBInteraction000536052
      WBInteraction000536054
      WBInteraction000536057
      WBInteraction000536087
      WBInteraction000536088
      WBInteraction000536089
      WBInteraction000536090
      WBInteraction000555819
    Anatomy_function: WBbtf0259
      WBbtf0260
      WBbtf0261
    WBProcess: WBbiopr:00000025
  Map_info: Map: II Position: 22.361 Error: 0.042113
    Well_ordered
    Positive: Positive_clone: W01G7 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 270
        416
        417
      Multi_point: 1396
        4984
  Reference (116)
  Remark: Sequence connection from [Edgley ML, Riddle DR]
  Method: Gene