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WormBase Tree Display for Gene: WBGene00000901

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Name Class

WBGene00000901EvidenceCGC_data_submission
SMapS_parentSequenceW01G7
IdentityVersion1
NameCGC_namedaf-5Person_evidenceWBPerson521
Sequence_nameW01G7.1
Molecular_nameW01G7.1
W01G7.1.1
CE18985
W01G7.1.2
Other_nameCELE_W01G7.1Accession_evidenceNDBBX284602
Public_namedaf-5
DB_infoDatabaseAceViewgene2O324
WormQTLgeneWBGene00000901
SignaLinkproteinWBGene00000901
WormFluxgeneWBGene00000901
NDBlocus_tagCELE_W01G7.1
PanthergeneCAEEL|WormBase=WBGene00000901|UniProtKB=G5EDM7
familyPTHR10005
NCBIgene175054
RefSeqproteinNM_064540.7
SwissProtUniProtAccG5EDM7
UniProt_GCRPUniProtAccG5EDM7
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdaf
Reference_alleleWBVar00143963
Allele (641)
Legacy_informatione1386 : defective dauer formation (daf-2 suppressible). ES1 ME3. NA11.
See also e1385, e1386
[C.elegansII] e1386 : defective dauer formation. ES1 ME3. OA11: e1385 etc. [Riddle et al. 1991; Thomas et al. 1993; DR]
StrainWBStrain00026946
WBStrain00030737
WBStrain00004317
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (28)
Structured_descriptionConcise_descriptiondaf-5 is an ortholog of human SKOR1 (SKI family transcriptional corepressor 1) and SKOR2 (SKI family transcriptional corepressor 2); daf-5 is involved in dauer entry, determination of adult lifespan, lipid storage, negative regulation of transcription from RNA polymerase II promoter, positive regulation of dauer larval development and transforming growth factor beta receptor signaling pathway; daf-5 is predicted to have SMAD binding activity, based on protein domain information; daf-5 is expressed in the muscle cell, gon_herm_dtc_P, gon_herm_dtc_A, certain interneurons, ganglion, hypodermis, intestine, and the head neurons; daf-5 is localized to the cytoplasm and the nucleus.Paper_evidence (18)
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated10 Apr 2017 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. Expressed in several structures, including XXX cell; ganglia; hermaphrodite distal tip cell; intestine; and muscle cell. Is an ortholog of human SKI (SKI proto-oncogene) and SKIL (SKI like proto-oncogene).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSW01G7.1
Corresponding_transcriptW01G7.1.1
W01G7.1.2
Other_sequenceLSC01469_1
CD203263.1
CR09984
CRC12262_1
Associated_feature (24)
Experimental_infoRNAi_result (17)
Expr_patternExpr2861
Expr2880
Expr2881
Expr1028726
Expr1030565
Expr1158077
Expr2010780
Expr2029017
Drives_constructWBCnstr00000991
WBCnstr00000992
WBCnstr00011005
WBCnstr00011006
WBCnstr00037209
Construct_productWBCnstr00011005
WBCnstr00037209
Microarray_results (20)
Expression_cluster (134)
Interaction (235)
Anatomy_functionWBbtf0259
WBbtf0260
WBbtf0261
WBProcessWBbiopr:00000025
Map_infoMapIIPosition22.361Error0.042113
Well_ordered
PositivePositive_cloneW01G7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point270
416
417
Multi_point1396
4984
ReferenceWBPaper00000316
WBPaper00000504
WBPaper00000608
WBPaper00000635
WBPaper00000680
WBPaper00000932
WBPaper00001393
WBPaper00001482
WBPaper00001774
WBPaper00001862
WBPaper00001942
WBPaper00002149
WBPaper00002485
WBPaper00002589
WBPaper00003019
WBPaper00003384
WBPaper00003854
WBPaper00004103
WBPaper00004310
WBPaper00004404
WBPaper00004405
WBPaper00004913
WBPaper00004925
WBPaper00005274
WBPaper00005511
WBPaper00006015
WBPaper00006042
WBPaper00006103
WBPaper00006272
WBPaper00006391
WBPaper00006425
WBPaper00010064
WBPaper00010252
WBPaper00010275
WBPaper00010290
WBPaper00010502
WBPaper00010552
WBPaper00010574
WBPaper00010707
WBPaper00010712
WBPaper00010911
WBPaper00012612
WBPaper00013396
WBPaper00014216
WBPaper00014658
WBPaper00014742
WBPaper00014743
WBPaper00014949
WBPaper00014950
WBPaper00015086
WBPaper00015209
WBPaper00015224
WBPaper00015225
WBPaper00015419
WBPaper00015800
WBPaper00016006
WBPaper00016327
WBPaper00017072
WBPaper00017331
WBPaper00017640
WBPaper00017937
WBPaper00018505
WBPaper00018513
WBPaper00018516
WBPaper00018762
WBPaper00019009
WBPaper00019048
WBPaper00021876
WBPaper00021886
WBPaper00021929
WBPaper00021985
WBPaper00022427
WBPaper00022779
WBPaper00022874
WBPaper00023261
WBPaper00023690
WBPaper00025980
WBPaper00026626
WBPaper00026632
WBPaper00026674
WBPaper00027186
WBPaper00027242
WBPaper00027256
WBPaper00027307
WBPaper00027346
WBPaper00028488
WBPaper00028750
WBPaper00028757
WBPaper00030571
WBPaper00031040
WBPaper00032181
WBPaper00033400
WBPaper00033845
WBPaper00034316
WBPaper00035152
WBPaper00035610
WBPaper00036529
WBPaper00038374
WBPaper00038985
WBPaper00042548
WBPaper00043775
WBPaper00043908
WBPaper00046789
WBPaper00047894
WBPaper00050267
WBPaper00052910
WBPaper00053566
WBPaper00059578
WBPaper00060365
WBPaper00060493
WBPaper00061671
WBPaper00061718
WBPaper00062125
WBPaper00063926
WBPaper00063938
WBPaper00066196
RemarkSequence connection from [Edgley ML, Riddle DR]
MethodGene