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WormBase Tree Display for Gene: WBGene00001006

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Name Class

WBGene00001006EvidenceCGC_data_submission
SMapS_parentSequenceC25F6
IdentityVersion1
NameCGC_namedlg-1
Sequence_nameC25F6.2
Molecular_nameC25F6.2
C25F6.2.1
CE36524
Other_nameCELE_C25F6.2Accession_evidenceNDBBX284606
Public_namedlg-1
DB_infoDatabaseAceViewgeneXG103
WormQTLgeneWBGene00001006
WormFluxgeneWBGene00001006
NDBlocus_tagCELE_C25F6.2
PanthergeneCAEEL|WormBase=WBGene00001006|UniProtKB=G5ECY0
familyPTHR23119
NCBIgene180819
RefSeqproteinNM_001029260.5
SwissProtUniProtAccG5ECY0
UniProt_GCRPUniProtAccG5ECY0
OMIMgene300189
602887
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:22WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdlg
AlleleWBVar00091616Inferred_automaticallyFrom strain object: SD1135
WBVar02158023
WBVar02158361
WBVar02158373
WBVar01147709
WBVar01147710
WBVar01147711
WBVar01147712
WBVar01758429
WBVar01147713
WBVar01758430
WBVar01758431
WBVar01147714
WBVar01147715
WBVar01147716
WBVar01147717
WBVar01147718
WBVar01147719
WBVar01147720
WBVar01147721
WBVar01147722
WBVar01147723
WBVar01147724
WBVar01147725
WBVar01147726
WBVar01147727
WBVar01879437
WBVar01879438
WBVar01147728
WBVar01147729
WBVar01879439
WBVar01147730
WBVar01879440
WBVar01147731
WBVar01879441
WBVar01147732
WBVar01879442
WBVar01879443
WBVar01147733
WBVar01879444
WBVar01147734
WBVar01879445
WBVar01147735
WBVar01879446
WBVar01147736
WBVar01147737
WBVar01879447
WBVar01147738
WBVar01819932
WBVar01819933
WBVar01819934
WBVar01819935
WBVar01819936
WBVar01830544
WBVar02063843
WBVar01549933
WBVar02063844
WBVar01549934
WBVar01549935
WBVar01549936
WBVar00503857
WBVar00503858
WBVar00503859
WBVar00503860
WBVar00503861
WBVar00503862
WBVar00503863
WBVar00503864
WBVar00503865
WBVar00503866
WBVar00503867
WBVar00503868
WBVar00503869
WBVar00503870
WBVar00503871
WBVar00503872
WBVar00503873
WBVar00503874
WBVar00503875
WBVar00503876
WBVar00503877
WBVar00503878
WBVar01945428
WBVar00079119
WBVar00079120
WBVar00079121
WBVar00079122
WBVar00079123
WBVar00275910
WBVar01147688
WBVar01147689
WBVar01147690
WBVar01147691
WBVar01147692
WBVar01147693
WBVar00599111
WBVar01147694
WBVar01147695
WBVar01147696
WBVar01147697
WBVar01147698
WBVar01147699
WBVar01147700
WBVar01147701
WBVar01147702
WBVar01147703
WBVar01147704
WBVar01147705
WBVar01147706
WBVar01147707
WBVar01500067
WBVar01147708
Possibly_affected_byWBVar02153212
StrainWBStrain00007529
WBStrain00033917
WBStrain00024324
WBStrain00026592
RNASeq_FPKM (74)
GO_annotation (35)
Ortholog (51)
ParalogWBGene00011890Caenorhabditis elegansFrom_analysisPanther
WBGene00017741Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptiondlg-1 encodes a MAGUK protein, orthologous to Drosophila Discs large; DLG-1 is physically located at apical adherens junctions in all epithelia and is required for organization of the embryonic gut epithelium into a coherent tube.Paper_evidenceWBPaper00004424
WBPaper00004510
WBPaper00006400
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated27 Jan 2012 00:00:00
Automated_descriptionPredicted to enable guanylate kinase activity. Involved in embryo development and zonula adherens assembly. Located in adherens junction and apical junction complex. Expressed in several structures, including arcade cell; germ line; intestine; pharyngeal cell; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease; cervix uteri carcinoma in situ; intellectual disability (multiple); and invasive ductal carcinoma. Is an ortholog of human DLG1 (discs large MAGUK scaffold protein 1); DLG3 (discs large MAGUK scaffold protein 3); and DLG4 (discs large MAGUK scaffold protein 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060307Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2903)
DOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2903)
DOID:8991Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2900)
DOID:3008Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2900)
DOID:0112041Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2902)
Molecular_infoCorresponding_CDSC25F6.2
Corresponding_CDS_historyC25F6.2a:wp121
C25F6.2b:wp271
Corresponding_transcriptC25F6.2.1
Other_sequence (86)
Associated_feature (29)
Experimental_infoRNAi_result (34)
Expr_pattern (15)
Drives_construct (17)
Construct_productWBCnstr00000944
WBCnstr00006155
WBCnstr00007873
WBCnstr00010311
WBCnstr00010468
WBCnstr00015686
WBCnstr00020203
WBCnstr00020897
WBCnstr00037145
WBCnstr00042006
AntibodyWBAntibody00000342
WBAntibody00000426
WBAntibody00000715
WBAntibody00000716
WBAntibody00000993
WBAntibody00001401
WBAntibody00001716
WBAntibody00001732
WBAntibody00002172
WBAntibody00002424
Microarray_results (27)
Expression_cluster (219)
Interaction (1194)
Map_infoMapXPosition-5.25173Error0.010511
PositivePositive_cloneC25F6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4261
4449
Pseudo_map_position
Reference (97)
RemarkSequence connection from [Bossinger O]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene