WormBase Tree Display for Gene: WBGene00001006
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WBGene00001006 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | C25F6 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | dlg-1 | |||||||
Sequence_name | C25F6.2 | ||||||||
Molecular_name | C25F6.2 | ||||||||
C25F6.2.1 | |||||||||
CE36524 | |||||||||
Other_name | CELE_C25F6.2 | Accession_evidence | NDB | BX284606 | |||||
Public_name | dlg-1 | ||||||||
DB_info | Database | AceView | gene | XG103 | |||||
WormQTL | gene | WBGene00001006 | |||||||
WormFlux | gene | WBGene00001006 | |||||||
NDB | locus_tag | CELE_C25F6.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00001006|UniProtKB=G5ECY0 | |||||||
family | PTHR23119 | ||||||||
NCBI | gene | 180819 | |||||||
RefSeq | protein | NM_001029260.5 | |||||||
SwissProt | UniProtAcc | G5ECY0 | |||||||
UniProt_GCRP | UniProtAcc | G5ECY0 | |||||||
OMIM | gene | 300189 | |||||||
602887 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | dlg | ||||||||
Allele | WBVar00091616 | Inferred_automatically | From strain object: SD1135 | ||||||
WBVar02158023 | |||||||||
WBVar02158361 | |||||||||
WBVar02158373 | |||||||||
WBVar01147709 | |||||||||
WBVar01147710 | |||||||||
WBVar01147711 | |||||||||
WBVar01147712 | |||||||||
WBVar01758429 | |||||||||
WBVar01147713 | |||||||||
WBVar01758430 | |||||||||
WBVar01758431 | |||||||||
WBVar01147714 | |||||||||
WBVar01147715 | |||||||||
WBVar01147716 | |||||||||
WBVar01147717 | |||||||||
WBVar01147718 | |||||||||
WBVar01147719 | |||||||||
WBVar01147720 | |||||||||
WBVar01147721 | |||||||||
WBVar01147722 | |||||||||
WBVar01147723 | |||||||||
WBVar01147724 | |||||||||
WBVar01147725 | |||||||||
WBVar01147726 | |||||||||
WBVar01147727 | |||||||||
WBVar01879437 | |||||||||
WBVar01879438 | |||||||||
WBVar01147728 | |||||||||
WBVar01147729 | |||||||||
WBVar01879439 | |||||||||
WBVar01147730 | |||||||||
WBVar01879440 | |||||||||
WBVar01147731 | |||||||||
WBVar01879441 | |||||||||
WBVar01147732 | |||||||||
WBVar01879442 | |||||||||
WBVar01879443 | |||||||||
WBVar01147733 | |||||||||
WBVar01879444 | |||||||||
WBVar01147734 | |||||||||
WBVar01879445 | |||||||||
WBVar01147735 | |||||||||
WBVar01879446 | |||||||||
WBVar01147736 | |||||||||
WBVar01147737 | |||||||||
WBVar01879447 | |||||||||
WBVar01147738 | |||||||||
WBVar01819932 | |||||||||
WBVar01819933 | |||||||||
WBVar01819934 | |||||||||
WBVar01819935 | |||||||||
WBVar01819936 | |||||||||
WBVar01830544 | |||||||||
WBVar02063843 | |||||||||
WBVar01549933 | |||||||||
WBVar02063844 | |||||||||
WBVar01549934 | |||||||||
WBVar01549935 | |||||||||
WBVar01549936 | |||||||||
WBVar00503857 | |||||||||
WBVar00503858 | |||||||||
WBVar00503859 | |||||||||
WBVar00503860 | |||||||||
WBVar00503861 | |||||||||
WBVar00503862 | |||||||||
WBVar00503863 | |||||||||
WBVar00503864 | |||||||||
WBVar00503865 | |||||||||
WBVar00503866 | |||||||||
WBVar00503867 | |||||||||
WBVar00503868 | |||||||||
WBVar00503869 | |||||||||
WBVar00503870 | |||||||||
WBVar00503871 | |||||||||
WBVar00503872 | |||||||||
WBVar00503873 | |||||||||
WBVar00503874 | |||||||||
WBVar00503875 | |||||||||
WBVar00503876 | |||||||||
WBVar00503877 | |||||||||
WBVar00503878 | |||||||||
WBVar01945428 | |||||||||
WBVar00079119 | |||||||||
WBVar00079120 | |||||||||
WBVar00079121 | |||||||||
WBVar00079122 | |||||||||
WBVar00079123 | |||||||||
WBVar00275910 | |||||||||
WBVar01147688 | |||||||||
WBVar01147689 | |||||||||
WBVar01147690 | |||||||||
WBVar01147691 | |||||||||
WBVar01147692 | |||||||||
WBVar01147693 | |||||||||
WBVar00599111 | |||||||||
WBVar01147694 | |||||||||
WBVar01147695 | |||||||||
WBVar01147696 | |||||||||
WBVar01147697 | |||||||||
WBVar01147698 | |||||||||
WBVar01147699 | |||||||||
WBVar01147700 | |||||||||
WBVar01147701 | |||||||||
WBVar01147702 | |||||||||
WBVar01147703 | |||||||||
WBVar01147704 | |||||||||
WBVar01147705 | |||||||||
WBVar01147706 | |||||||||
WBVar01147707 | |||||||||
WBVar01500067 | |||||||||
WBVar01147708 | |||||||||
Possibly_affected_by | WBVar02153212 | ||||||||
Strain | WBStrain00007529 | ||||||||
WBStrain00033917 | |||||||||
WBStrain00024324 | |||||||||
WBStrain00026592 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (35) | |||||||||
Ortholog (51) | |||||||||
Paralog | WBGene00011890 | Caenorhabditis elegans | From_analysis | Panther | |||||
WBGene00017741 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
Structured_description | Concise_description | dlg-1 encodes a MAGUK protein, orthologous to Drosophila Discs large; DLG-1 is physically located at apical adherens junctions in all epithelia and is required for organization of the embryonic gut epithelium into a coherent tube. | Paper_evidence | WBPaper00004424 | |||||
WBPaper00004510 | |||||||||
WBPaper00006400 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 27 Jan 2012 00:00:00 | ||||||||
Automated_description | Predicted to enable guanylate kinase activity. Involved in embryo development and zonula adherens assembly. Located in adherens junction and apical junction complex. Expressed in several structures, including arcade cell; germ line; intestine; pharyngeal cell; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease; cervix uteri carcinoma in situ; intellectual disability (multiple); and invasive ductal carcinoma. Is an ortholog of human DLG1 (discs large MAGUK scaffold protein 1); DLG3 (discs large MAGUK scaffold protein 3); and DLG4 (discs large MAGUK scaffold protein 4). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0060307 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2903) | ||||
DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2903) | ||||||
DOID:8991 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2900) | ||||||
DOID:3008 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2900) | ||||||
DOID:0112041 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2902) | ||||||
Molecular_info | Corresponding_CDS | C25F6.2 | |||||||
Corresponding_CDS_history | C25F6.2a:wp121 | ||||||||
C25F6.2b:wp271 | |||||||||
Corresponding_transcript | C25F6.2.1 | ||||||||
Other_sequence (86) | |||||||||
Associated_feature (29) | |||||||||
Experimental_info | RNAi_result (34) | ||||||||
Expr_pattern (15) | |||||||||
Drives_construct (17) | |||||||||
Construct_product | WBCnstr00000944 | ||||||||
WBCnstr00006155 | |||||||||
WBCnstr00007873 | |||||||||
WBCnstr00010311 | |||||||||
WBCnstr00010468 | |||||||||
WBCnstr00015686 | |||||||||
WBCnstr00020203 | |||||||||
WBCnstr00020897 | |||||||||
WBCnstr00037145 | |||||||||
WBCnstr00042006 | |||||||||
Antibody | WBAntibody00000342 | ||||||||
WBAntibody00000426 | |||||||||
WBAntibody00000715 | |||||||||
WBAntibody00000716 | |||||||||
WBAntibody00000993 | |||||||||
WBAntibody00001401 | |||||||||
WBAntibody00001716 | |||||||||
WBAntibody00001732 | |||||||||
WBAntibody00002172 | |||||||||
WBAntibody00002424 | |||||||||
Microarray_results (27) | |||||||||
Expression_cluster (219) | |||||||||
Interaction (1194) | |||||||||
Map_info | Map | X | Position | -5.25173 | Error | 0.010511 | |||
Positive | Positive_clone | C25F6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4261 | |||||||
4449 | |||||||||
Pseudo_map_position | |||||||||
Reference (97) | |||||||||
Remark | Sequence connection from [Bossinger O] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |