WormBase Tree Display for Gene: WBGene00001006
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| WBGene00001006 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C25F6 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | dlg-1 | |||||||
| Sequence_name | C25F6.2 | ||||||||
| Molecular_name | C25F6.2 | ||||||||
| C25F6.2.1 | |||||||||
| CE36524 | |||||||||
| Other_name | CELE_C25F6.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | dlg-1 | ||||||||
| DB_info | Database | AceView | gene | XG103 | |||||
| WormQTL | gene | WBGene00001006 | |||||||
| WormFlux | gene | WBGene00001006 | |||||||
| NDB | locus_tag | CELE_C25F6.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001006|UniProtKB=G5ECY0 | |||||||
| family | PTHR23119 | ||||||||
| NCBI | gene | 180819 | |||||||
| RefSeq | protein | NM_001029260.5 | |||||||
| SwissProt | UniProtAcc | G5ECY0 | |||||||
| UniProt_GCRP | UniProtAcc | G5ECY0 | |||||||
| OMIM | gene | 300189 | |||||||
| 602887 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:22 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dlg | ||||||||
| Allele (112) | |||||||||
| Possibly_affected_by | WBVar02153212 | ||||||||
| Strain | WBStrain00007529 | ||||||||
| WBStrain00033917 | |||||||||
| WBStrain00024324 | |||||||||
| WBStrain00026592 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (35) | |||||||||
| Ortholog (51) | |||||||||
| Paralog | WBGene00011890 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00017741 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | dlg-1 encodes a MAGUK protein, orthologous to Drosophila Discs large; DLG-1 is physically located at apical adherens junctions in all epithelia and is required for organization of the embryonic gut epithelium into a coherent tube. | Paper_evidence | WBPaper00004424 | |||||
| WBPaper00004510 | |||||||||
| WBPaper00006400 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 27 Jan 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable guanylate kinase activity. Involved in embryo development and zonula adherens assembly. Located in adherens junction and apical junction complex. Expressed in several structures, including arcade cell; germ line; intestine; pharyngeal cell; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease; cervix uteri carcinoma in situ; intellectual disability (multiple); and invasive ductal carcinoma. Is an ortholog of human DLG1 (discs large MAGUK scaffold protein 1); DLG3 (discs large MAGUK scaffold protein 3); and DLG4 (discs large MAGUK scaffold protein 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060307 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2903) | ||||
| DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2903) | ||||||
| DOID:8991 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2900) | ||||||
| DOID:3008 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2900) | ||||||
| DOID:0112041 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2902) | ||||||
| Molecular_info | Corresponding_CDS | C25F6.2 | |||||||
| Corresponding_CDS_history | C25F6.2a:wp121 | ||||||||
| C25F6.2b:wp271 | |||||||||
| Corresponding_transcript | C25F6.2.1 | ||||||||
| Other_sequence (86) | |||||||||
| Associated_feature (29) | |||||||||
| Experimental_info | RNAi_result (34) | ||||||||
| Expr_pattern (15) | |||||||||
| Drives_construct (17) | |||||||||
| Construct_product | WBCnstr00000944 | ||||||||
| WBCnstr00006155 | |||||||||
| WBCnstr00007873 | |||||||||
| WBCnstr00010311 | |||||||||
| WBCnstr00010468 | |||||||||
| WBCnstr00015686 | |||||||||
| WBCnstr00020203 | |||||||||
| WBCnstr00020897 | |||||||||
| WBCnstr00037145 | |||||||||
| WBCnstr00042006 | |||||||||
| Antibody | WBAntibody00000342 | ||||||||
| WBAntibody00000426 | |||||||||
| WBAntibody00000715 | |||||||||
| WBAntibody00000716 | |||||||||
| WBAntibody00000993 | |||||||||
| WBAntibody00001401 | |||||||||
| WBAntibody00001716 | |||||||||
| WBAntibody00001732 | |||||||||
| WBAntibody00002172 | |||||||||
| WBAntibody00002424 | |||||||||
| Microarray_results (27) | |||||||||
| Expression_cluster (219) | |||||||||
| Interaction (1194) | |||||||||
| Map_info | Map | X | Position | -5.25173 | Error | 0.010511 | |||
| Positive | Positive_clone | C25F6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4261 | |||||||
| 4449 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00004510 | ||||||||
| WBPaper00004765 | |||||||||
| WBPaper00004780 | |||||||||
| WBPaper00004961 | |||||||||
| WBPaper00004964 | |||||||||
| WBPaper00005372 | |||||||||
| WBPaper00005576 | |||||||||
| WBPaper00005969 | |||||||||
| WBPaper00005975 | |||||||||
| WBPaper00006196 | |||||||||
| WBPaper00006400 | |||||||||
| WBPaper00006422 | |||||||||
| WBPaper00006462 | |||||||||
| WBPaper00006463 | |||||||||
| WBPaper00011311 | |||||||||
| WBPaper00011601 | |||||||||
| WBPaper00012331 | |||||||||
| WBPaper00013425 | |||||||||
| WBPaper00016966 | |||||||||
| WBPaper00017617 | |||||||||
| WBPaper00017731 | |||||||||
| WBPaper00017732 | |||||||||
| WBPaper00017733 | |||||||||
| WBPaper00017734 | |||||||||
| WBPaper00018116 | |||||||||
| WBPaper00018120 | |||||||||
| WBPaper00018122 | |||||||||
| WBPaper00019574 | |||||||||
| WBPaper00019576 | |||||||||
| WBPaper00024200 | |||||||||
| WBPaper00024261 | |||||||||
| WBPaper00024738 | |||||||||
| WBPaper00024816 | |||||||||
| WBPaper00024817 | |||||||||
| WBPaper00027155 | |||||||||
| WBPaper00027244 | |||||||||
| WBPaper00027245 | |||||||||
| WBPaper00027414 | |||||||||
| WBPaper00029033 | |||||||||
| WBPaper00029128 | |||||||||
| WBPaper00030521 | |||||||||
| WBPaper00030629 | |||||||||
| WBPaper00031185 | |||||||||
| WBPaper00031697 | |||||||||
| WBPaper00032108 | |||||||||
| WBPaper00032115 | |||||||||
| WBPaper00032233 | |||||||||
| WBPaper00032467 | |||||||||
| WBPaper00033350 | |||||||||
| WBPaper00035600 | |||||||||
| WBPaper00036023 | |||||||||
| WBPaper00036179 | |||||||||
| WBPaper00036205 | |||||||||
| WBPaper00036843 | |||||||||
| WBPaper00036871 | |||||||||
| WBPaper00036979 | |||||||||
| WBPaper00037766 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00038628 | |||||||||
| WBPaper00038669 | |||||||||
| WBPaper00039779 | |||||||||
| WBPaper00039809 | |||||||||
| WBPaper00040999 | |||||||||
| WBPaper00042762 | |||||||||
| WBPaper00042878 | |||||||||
| WBPaper00045462 | |||||||||
| WBPaper00046645 | |||||||||
| WBPaper00049111 | |||||||||
| WBPaper00050170 | |||||||||
| WBPaper00051293 | |||||||||
| WBPaper00051878 | |||||||||
| WBPaper00052187 | |||||||||
| WBPaper00053439 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00056223 | |||||||||
| WBPaper00056902 | |||||||||
| WBPaper00056919 | |||||||||
| WBPaper00057738 | |||||||||
| WBPaper00057739 | |||||||||
| WBPaper00058130 | |||||||||
| WBPaper00058724 | |||||||||
| WBPaper00059330 | |||||||||
| WBPaper00059613 | |||||||||
| WBPaper00060754 | |||||||||
| WBPaper00060787 | |||||||||
| WBPaper00060888 | |||||||||
| WBPaper00062058 | |||||||||
| WBPaper00062161 | |||||||||
| WBPaper00062248 | |||||||||
| WBPaper00063007 | |||||||||
| WBPaper00063074 | |||||||||
| WBPaper00064105 | |||||||||
| WBPaper00064182 | |||||||||
| WBPaper00064587 | |||||||||
| WBPaper00064685 | |||||||||
| WBPaper00064911 | |||||||||
| WBPaper00065282 | |||||||||
| Remark | Sequence connection from [Bossinger O] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
