WormBase Tree Display for Gene: WBGene00001073

WBGene00001073 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F46E10
  Identity: Version: 1
    Name: CGC_name: dpy-11 Person_evidence: WBPerson261
      Sequence_name: F46E10.9
      Molecular_name: F46E10.9
        F46E10.9.1
        CE20819
        F46E10.9.2
      Other_name: CELE_F46E10.9 Accession_evidence: NDB BX284605
      Public_name: dpy-11
    DB_info: Database: AceView gene 5G992
        WormQTL gene WBGene00001073
        WormFlux gene WBGene00001073
        NDB locus_tag CELE_F46E10.9
        Panther gene CAEEL|WormBase=WBGene00001073|UniProtKB=G5EC91
          family PTHR46107
        NCBI gene 179040
        RefSeq protein NM_001383321.2
        TREEFAM TREEFAM_ID TF106376
        TrEMBL UniProtAcc G5EC91
        UniProt_GCRP UniProtAcc G5EC91
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:22 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dpy
    Reference_allele: WBVar00143044
    Allele (97)
    Legacy_information: e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. NA > 10 (e33 e1180icr (these and most other alleles have much stronger dumpy ('piggy') phenotype) etc.).
      See also e33, e752, e1180, e1194, s360
      [C.elegansII] e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. Males Ram (lumpy rays) at25C. OA>10: e33, e1180icr (these and most other alleles have much stronger dumpy or 'piggy' phenotype) etc.), e455,e733, e752, s287 (induced on eT1), s10, s261, s360fdi etc. [Brenner 1974; Baird and Emmons 1990; CB]
    Strain (139)
    RNASeq_FPKM (74)
    GO_annotation: 00011338
      00011339
      00011340
      00011341
      00011342
      00011343
      00011344
      00011345
      00011346
    Contained_in_operon: CEOP5120
    Ortholog (41)
    Paralog (14)
    Structured_description: Automated_description: Enables protein-disulfide reductase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; post-embryonic body morphogenesis; and protein folding. Located in endomembrane system. Expressed in several structures, including R1_hyp; R2_hyp; R3_hyp; R4_hyp; and R5_hyp. Is an ortholog of human TMX1 (thioredoxin related transmembrane protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F46E10.9
    Corresponding_transcript: F46E10.9.1
      F46E10.9.2
    Other_sequence (67)
    Associated_feature (20)
  Experimental_info: RNAi_result (20)
    Expr_pattern: Chronogram1745
      Expr1854
      Expr1855
      Expr6089
      Expr13275
      Expr1026593
      Expr1030681
      Expr1151367
      Expr2011056
      Expr2029293
    Drives_construct: WBCnstr00002463
      WBCnstr00010487
      WBCnstr00010488
      WBCnstr00042718
    Construct_product: WBCnstr00010488
    Microarray_results (22)
    Expression_cluster (192)
    Interaction: WBInteraction000001623
      WBInteraction000002651
      WBInteraction000004827
      WBInteraction000028859
      WBInteraction000030342
      WBInteraction000030343
      WBInteraction000052057
      WBInteraction000052372
      WBInteraction000052482
      WBInteraction000052500
      WBInteraction000052504
      WBInteraction000052523
      WBInteraction000052524
      WBInteraction000052525
      WBInteraction000052526
      WBInteraction000052530
      WBInteraction000052546
      WBInteraction000052553
      WBInteraction000121196
      WBInteraction000133383
      WBInteraction000142017
      WBInteraction000142451
      WBInteraction000148647
      WBInteraction000149516
      WBInteraction000149837
      WBInteraction000151380
      WBInteraction000156773
      WBInteraction000161264
      WBInteraction000164201
      WBInteraction000165683
      WBInteraction000178882
      WBInteraction000179627
      WBInteraction000179628
      WBInteraction000179643
      WBInteraction000181399
      WBInteraction000187594
      WBInteraction000191519
      WBInteraction000191520
      WBInteraction000191938
      WBInteraction000193052
      WBInteraction000196879
      WBInteraction000197975
      WBInteraction000200094
      WBInteraction000200569
      WBInteraction000202347
      WBInteraction000202359
      WBInteraction000203133
      WBInteraction000206734
      WBInteraction000207607
      WBInteraction000208136
      WBInteraction000209816
      WBInteraction000209931
      WBInteraction000212961
      WBInteraction000214091
      WBInteraction000215026
      WBInteraction000215135
      WBInteraction000215639
      WBInteraction000216259
      WBInteraction000216844
      WBInteraction000218498
      WBInteraction000222500
      WBInteraction000224191
      WBInteraction000228736
      WBInteraction000230392
      WBInteraction000230912
      WBInteraction000237678
      WBInteraction000237982
      WBInteraction000244306
      WBInteraction000248401
      WBInteraction000248971
      WBInteraction000252594
      WBInteraction000253073
      WBInteraction000254249
      WBInteraction000256106
      WBInteraction000257052
      WBInteraction000257247
      WBInteraction000259930
      WBInteraction000260058
      WBInteraction000265105
      WBInteraction000268618
      WBInteraction000269490
      WBInteraction000280059
      WBInteraction000281010
      WBInteraction000281728
      WBInteraction000284563
      WBInteraction000286643
      WBInteraction000289510
      WBInteraction000291153
      WBInteraction000295834
      WBInteraction000296029
      WBInteraction000299402
      WBInteraction000301342
      WBInteraction000311499
      WBInteraction000315530
      WBInteraction000316678
      WBInteraction000321630
      WBInteraction000322282
      WBInteraction000323179
      WBInteraction000323721
      WBInteraction000325169
      WBInteraction000327713
      WBInteraction000339957
      WBInteraction000343416
      WBInteraction000346044
      WBInteraction000346838
      WBInteraction000354877
      WBInteraction000355043
      WBInteraction000359200
      WBInteraction000361021
      WBInteraction000366045
      WBInteraction000368477
      WBInteraction000370050
      WBInteraction000375874
      WBInteraction000378761
      WBInteraction000380502
      WBInteraction000386990
      WBInteraction000387352
      WBInteraction000391605
      WBInteraction000395621
      WBInteraction000399009
      WBInteraction000407044
      WBInteraction000411055
      WBInteraction000411587
      WBInteraction000413069
      WBInteraction000414907
      WBInteraction000415149
      WBInteraction000415816
      WBInteraction000420727
      WBInteraction000423107
      WBInteraction000425877
      WBInteraction000432037
      WBInteraction000432581
      WBInteraction000433807
      WBInteraction000446322
      WBInteraction000447760
      WBInteraction000451169
      WBInteraction000457199
      WBInteraction000458161
      WBInteraction000465041
      WBInteraction000470568
      WBInteraction000511581
      WBInteraction000515685
      WBInteraction000537295
      WBInteraction000537296
      WBInteraction000537327
      WBInteraction000543737
      WBInteraction000543785
      WBInteraction000559289
      WBInteraction000563089
      WBInteraction000563566
      WBInteraction000573403
      WBInteraction000574507
      WBInteraction000577539
      WBInteraction000579963
      WBInteraction000586015
    WBProcess: WBbiopr:00000124
  Map_info: Map: V Position: 0
    Well_ordered
    Positive: Inside_rearr: sDf20
        sDf30
        nDf1
        nDf18
        rT1
      Positive_clone: F46E10 Inferred_automatically: From sequence, transcript, pseudogene data
        T04F11
    Negative: Outside_rearr: sDf36
        eDf1
        nDf42
      Negative_clone: W01A11
    Mapping_data: 2_point (100)
      Multi_point (259)
      Pos_neg_data (15)
    Landmark_gene
  Reference (113)
  Remark: Julia Pak rescued dpy-11 with T04F11 when she was a rotation student in my lab.
    Sequence connection from [Ko F]
  Method: Gene