WormBase Tree Display for Gene: WBGene00001073

WBGene00001073 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F46E10
  Identity: Version: 1
    Name: CGC_name: dpy-11 Person_evidence: WBPerson261
      Sequence_name: F46E10.9
      Molecular_name: F46E10.9
        F46E10.9.1
        CE20819
        F46E10.9.2
      Other_name: CELE_F46E10.9 Accession_evidence: NDB BX284605
      Public_name: dpy-11
    DB_info: Database: AceView gene 5G992
        WormQTL gene WBGene00001073
        WormFlux gene WBGene00001073
        NDB locus_tag CELE_F46E10.9
        Panther gene CAEEL|WormBase=WBGene00001073|UniProtKB=G5EC91
          family PTHR46107
        NCBI gene 179040
        RefSeq protein NM_001383321.2
        TREEFAM TREEFAM_ID TF106376
        TrEMBL UniProtAcc G5EC91
        UniProt_GCRP UniProtAcc G5EC91
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:22 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dpy
    Reference_allele: WBVar00143044
    Allele (97)
    Legacy_information: e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. NA > 10 (e33 e1180icr (these and most other alleles have much stronger dumpy ('piggy') phenotype) etc.).
      See also e33, e752, e1180, e1194, s360
      [C.elegansII] e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. Males Ram (lumpy rays) at25C. OA>10: e33, e1180icr (these and most other alleles have much stronger dumpy or 'piggy' phenotype) etc.), e455,e733, e752, s287 (induced on eT1), s10, s261, s360fdi etc. [Brenner 1974; Baird and Emmons 1990; CB]
    Strain: WBStrain00029457
      WBStrain00022203
      WBStrain00022204
      WBStrain00022205
      WBStrain00022475
      WBStrain00022581
      WBStrain00022601
      WBStrain00022763
      WBStrain00023813
      WBStrain00024119
      WBStrain00026734
      WBStrain00026769
      WBStrain00026886
      WBStrain00026980
      WBStrain00026981
      WBStrain00026982
      WBStrain00026983
      WBStrain00027012
      WBStrain00027135
      WBStrain00027611
      WBStrain00029050
      WBStrain00029138
      WBStrain00029139
      WBStrain00029140
      WBStrain00029456
      WBStrain00029464
      WBStrain00029552
      WBStrain00030581
      WBStrain00031248
      WBStrain00031249
      WBStrain00033526
      WBStrain00034134
      WBStrain00034200
      WBStrain00034360
      WBStrain00034440
      WBStrain00034446
      WBStrain00034447
      WBStrain00034448
      WBStrain00034455
      WBStrain00034456
      WBStrain00034712
      WBStrain00035101
      WBStrain00035709
      WBStrain00000374
      WBStrain00000532
      WBStrain00000533
      WBStrain00000534
      WBStrain00000598
      WBStrain00000599
      WBStrain00000600
      WBStrain00000601
      WBStrain00000602
      WBStrain00000603
      WBStrain00000604
      WBStrain00000607
      WBStrain00000608
      WBStrain00000609
      WBStrain00000610
      WBStrain00000484
      WBStrain00000631
      WBStrain00000632
      WBStrain00000633
      WBStrain00000634
      WBStrain00000637
      WBStrain00000638
      WBStrain00000639
      WBStrain00000640
      WBStrain00000641
      WBStrain00000661
      WBStrain00000489
      WBStrain00003994
      WBStrain00004263
      WBStrain00004365
      WBStrain00004367
      WBStrain00004128
      WBStrain00004374
      WBStrain00004379
      WBStrain00004386
      WBStrain00004130
      WBStrain00004400
      WBStrain00004497
      WBStrain00004547
      WBStrain00004567
      WBStrain00004944
      WBStrain00004946
      WBStrain00004960
      WBStrain00004964
      WBStrain00004970
      WBStrain00004993
      WBStrain00005001
      WBStrain00005004
      WBStrain00005458
      WBStrain00005874
      WBStrain00006189
      WBStrain00006195
      WBStrain00006196
      WBStrain00006197
      WBStrain00006211
      WBStrain00006212
      WBStrain00006218
      WBStrain00006234
      WBStrain00006235
      WBStrain00006250
      WBStrain00006666
      WBStrain00007270
      WBStrain00007454
      WBStrain00007455
      WBStrain00007456
      WBStrain00007493
      WBStrain00007745
      WBStrain00007982
      WBStrain00008000
      WBStrain00008001
      WBStrain00008003
      WBStrain00008004
      WBStrain00008276
      WBStrain00008414
      WBStrain00040642
      WBStrain00007457
      WBStrain00050644
      WBStrain00050645
      WBStrain00007773
      WBStrain00004002
      WBStrain00051662
      WBStrain00051663
      WBStrain00051683
      WBStrain00051676
      WBStrain00051684
      WBStrain00051675
      WBStrain00051672
      WBStrain00051671
      WBStrain00051673
      WBStrain00051664
      WBStrain00051666
      WBStrain00051665
      WBStrain00051681
      WBStrain00051667
      WBStrain00051682
      WBStrain00051677
    RNASeq_FPKM (74)
    GO_annotation: 00011338
      00011339
      00011340
      00011341
      00011342
      00011343
      00011344
      00011345
      00011346
    Contained_in_operon: CEOP5120
    Ortholog (41)
    Paralog (14)
    Structured_description: Automated_description: Enables protein-disulfide reductase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; post-embryonic body morphogenesis; and protein folding. Located in endomembrane system. Expressed in several structures, including R1_hyp; R2_hyp; R3_hyp; R4_hyp; and R5_hyp. Is an ortholog of human TMX1 (thioredoxin related transmembrane protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F46E10.9
    Corresponding_transcript: F46E10.9.1
      F46E10.9.2
    Other_sequence (67)
    Associated_feature (20)
  Experimental_info: RNAi_result (20)
    Expr_pattern: Chronogram1745
      Expr1854
      Expr1855
      Expr6089
      Expr13275
      Expr1026593
      Expr1030681
      Expr1151367
      Expr2011056
      Expr2029293
    Drives_construct: WBCnstr00002463
      WBCnstr00010487
      WBCnstr00010488
      WBCnstr00042718
    Construct_product: WBCnstr00010488
    Microarray_results (22)
    Expression_cluster (192)
    Interaction (155)
    WBProcess: WBbiopr:00000124
  Map_info: Map: V Position: 0
    Well_ordered
    Positive: Inside_rearr: sDf20
        sDf30
        nDf1
        nDf18
        rT1
      Positive_clone: F46E10 Inferred_automatically: From sequence, transcript, pseudogene data
        T04F11
    Negative: Outside_rearr: sDf36
        eDf1
        nDf42
      Negative_clone: W01A11
    Mapping_data: 2_point (100)
      Multi_point (259)
      Pos_neg_data (15)
    Landmark_gene
  Reference (113)
  Remark: Julia Pak rescued dpy-11 with T04F11 when she was a rotation student in my lab.
    Sequence connection from [Ko F]
  Method: Gene