WormBase Tree Display for Gene: WBGene00001078
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| WBGene00001078 | SMap | S_parent | Sequence | F22B7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | dpy-19 | Person_evidence | WBPerson261 | |||||
| Sequence_name | F22B7.10 | ||||||||
| Molecular_name | F22B7.10 | ||||||||
| F22B7.10.1 | |||||||||
| CE26462 | |||||||||
| Other_name | CELE_F22B7.10 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | dpy-19 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:23 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dpy | ||||||||
| Reference_allele | WBVar00143868 | ||||||||
| Allele (97) | |||||||||
| Possibly_affected_by | WBVar02152925 | ||||||||
| Legacy_information | e1259ts des mat : dumpy (20x 25x) wildtype (15x). ES3 (adult 25x). Weaker phenotype if mother dpy-19/+. ME0 (25x) ME3 (15x). NA2 (e1314ts). | ||||||||
| [C.elegansII] e1259ts,des,mat : dumpy (20C, 25C); WT (15C); abnormal Q and Q daughter migrations.ES3 (adult 25C). Weaker phenotype if mother dpy-19/+. ME0 (25C) ME3 (15C). OA3: e1314ts, n1347, pk102[DR; MT; CF] | |||||||||
| Strain (187) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (40) | |||||||||
| Structured_description | Concise_description | dpy-19 encodes a C-mannosyltransferase; DPY-19 is required for mannosylation of the surface receptors MIG-21 and UNC-5, and for correct polarization and migration of the neuroblasts QL and QR. | Paper_evidence | WBPaper00004437 | |||||
| WBPaper00042218 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 11 Apr 2013 00:00:00 | ||||||||
| Automated_description | Enables mannosyltransferase activity. Predicted to be involved in carbohydrate metabolic process; cell differentiation; and nervous system development. Located in perinuclear region of cytoplasm. Expressed in several structures, including P1; P2; QL; QR; and seam cell. Human ortholog(s) of this gene implicated in spermatogenic failure 9. Is an ortholog of human DPY19L2 (dpy-19 like 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111156 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19414) | ||||
| Molecular_info | Corresponding_CDS | F22B7.10 | |||||||
| Corresponding_transcript | F22B7.10.1 | ||||||||
| Other_sequence (16) | |||||||||
| Associated_feature (14) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00092898 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00013734 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00045288 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005460 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1835 | ||||||||
| Expr1836 | |||||||||
| Expr14861 | |||||||||
| Expr14862 | |||||||||
| Expr1022110 | |||||||||
| Expr1030686 | |||||||||
| Expr1149215 | |||||||||
| Expr2011061 | |||||||||
| Expr2029298 | |||||||||
| Drives_construct | WBCnstr00010476 | ||||||||
| WBCnstr00010477 | |||||||||
| WBCnstr00037094 | |||||||||
| Construct_product | WBCnstr00010476 | ||||||||
| WBCnstr00037094 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (115) | |||||||||
| Interaction (29) | |||||||||
| Map_info | Map | III | Position | -0.190874 | Error | 0.004839 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | nDf20 | |||||||
| nDf21 | |||||||||
| nDf22 | |||||||||
| nDp2 | |||||||||
| Positive_clone | F22B7 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| Negative | Outside_rearr | tnDf2 | |||||||
| Mapping_data | 2_point | 278 | |||||||
| Multi_point (65) | |||||||||
| Pos_neg_data | 802 | ||||||||
| 810 | |||||||||
| 812 | |||||||||
| 1618 | |||||||||
| 5742 | |||||||||
| 8635 | |||||||||
| 8799 | |||||||||
| 8825 | |||||||||
| 9449 | |||||||||
| Reference (44) | |||||||||
| Remark | [ Sean Collums and Ronald Plasterk] dpy-19 = F22B7.10. They detected a polymorphism in F22B7.10 in the Tc1 allele dpy-19(n1347).[sdm 12/00] | ||||||||
| Method | Gene |
