WormBase Tree Display for Gene: WBGene00001413
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| WBGene00001413 | SMap | S_parent | Sequence | C01F6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | fem-3 | Person_evidence | WBPerson261 | |||||
| Sequence_name | C01F6.4 | ||||||||
| Molecular_name | C01F6.4a | ||||||||
| C01F6.4a.1 | |||||||||
| CE02953 | |||||||||
| C01F6.4c | |||||||||
| CE46813 | |||||||||
| C01F6.4b | |||||||||
| C01F6.4c.1 | |||||||||
| Other_name | CELE_C01F6.4 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | fem-3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | fem | ||||||||
| Reference_allele | WBVar00144465 | ||||||||
| WBVar00240985 | |||||||||
| Allele (71) | |||||||||
| Legacy_information | Class 1 (loss-of-function) : e1996sd mat : XO animals transformed into fertile females if mother homozygous e1996 into intersexes if mother heterozygous e1996/+; XX animals fertile females. Some e1996/+ XX animals female. Some e1996/+ sons of e1996 mothers are feminized. ES3 (XO adult) ES2 (XX adult). ME0. NA > 20 (e1950 e2006ts : XX self-fertile at 20x). | ||||||||
| Class 2 (gain-of-function) : q20sd ts : at 25x XX germline makes only sperm at 15x XX germline makes oocytes and excess sperm. ES3 (progeny) ME3. NA9 (q24 etc. : all ts). | |||||||||
| See also e1950, e1980, e1981, e1983, e1984, e1995, e1996, e1999, e2004, e2006, e2007, e2010, e2043, e2045, e2062, e2063, e2068, e2070, e2143, e2178, e2289, e2353, e2354, e2366 | |||||||||
| [C.elegansII] e1996sd,mat,och : XO animals transformed into fertile females if mother homozygous, into intersexes if mother heterozygous; XX animals fertile females. Some e1996/+ XX animals female. Some e1996/+ sons of e1996 mothers are feminized. ES3 (XO adult) ES2 (XX adult). ME0. OA>20 e1950, e2068amb, e2006ts (XX self-fertile at 20C). Also gf,ts alleles, q20sd,ts (at 25C XX germline makes only sperm, at 15C XX germline makes oocytes and excess sperm. ES3 (progeny) ME3. OA8(gf):q22ts (weaker), q95ts (strongest allele, 80% Mog even at 15C). Cloned: 1.7 kb and 1.55 kb (minor) transcripts, former encodes predicted 388 aa novel protein. gf alleles are alterations in 3'UTR. Transgene overexpression of fem-3 leads to extensive masculinization of XX soma. [Hodgkin 1986; Ahringer et al. 1992; CB; JK; AS] | |||||||||
| Strain (12) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (26) | |||||||||
| Ortholog (21) | |||||||||
| Structured_description | Concise_description | fem-3 encodes a novel protein that promotes male development in all tissues. | Paper_evidence | WBPaper00001378 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 Apr 2005 00:00:00 | ||||||||
| Automated_description | Enables protein phosphatase binding activity. Involved in several processes, including protein localization to chromatin; regulation of reproductive process; and sex determination. Located in cytoplasm and protein-containing complex. Expressed in germ line; spermatid; and in male. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C01F6.4a | |||||||
| C01F6.4c | |||||||||
| Corresponding_transcript | C01F6.4b | ||||||||
| C01F6.4a.1 | |||||||||
| C01F6.4c.1 | |||||||||
| Other_sequence | X64962 | ||||||||
| CBC07169_1 | |||||||||
| Associated_feature | WBsf660472 | ||||||||
| WBsf997355 | |||||||||
| WBsf1017925 | |||||||||
| WBsf228786 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00061018 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00030242 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00039313 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00087453 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007588 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00081939 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00081938 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085808 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1382 | ||||||||
| Expr3829 | |||||||||
| Expr9317 | |||||||||
| Expr1021877 | |||||||||
| Expr1030847 | |||||||||
| Expr1143426 | |||||||||
| Expr2011751 | |||||||||
| Expr2029989 | |||||||||
| Drives_construct | WBCnstr00011680 | ||||||||
| WBCnstr00018576 | |||||||||
| WBCnstr00036963 | |||||||||
| Construct_product (17) | |||||||||
| Antibody | WBAntibody00002227 | ||||||||
| WBAntibody00002344 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (154) | |||||||||
| Interaction (421) | |||||||||
| WBProcess | WBbiopr:00000110 | ||||||||
| Map_info | Map | IV | Position | 4.04953 | Error | 0.001985 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | eDf18 | |||||||
| eDf19 | |||||||||
| Positive_clone | C01F6 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| JK#2 | |||||||||
| Mapping_data | 2_point | 1640 | |||||||
| Multi_point (14) | |||||||||
| Pos_neg_data | 959 | ||||||||
| 964 | |||||||||
| 972 | |||||||||
| Landmark_gene | |||||||||
| Reference (401) | |||||||||
| Picture | WBPicture0000013095 | ||||||||
| Method | Gene |
