WormBase Tree Display for Gene: WBGene00001518
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WBGene00001518 | SMap | S_parent | Sequence | F47D12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | gar-2 | Person_evidence | WBPerson32 | |||||
Sequence_name | F47D12.1 | ||||||||
Molecular_name (15) | |||||||||
Other_name | acm-2 | Paper_evidence | WBPaper00027767 | ||||||
From_analysis | WormAtlas | ||||||||
CELE_F47D12.1 | Accession_evidence | NDB | BX284603 | ||||||
Public_name | gar-2 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
2 | 10 Jun 2014 12:12:12 | WBPerson1983 | Event | Acquires_merge | WBGene00043340 | ||||
Acquires_merge | WBGene00043340 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | gar | ||||||||
Allele (131) | |||||||||
Strain | WBStrain00003713 | ||||||||
WBStrain00031470 | |||||||||
WBStrain00022222 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (37) | |||||||||
Ortholog (32) | |||||||||
Paralog (20) | |||||||||
Structured_description | Concise_description | gar-2 encodes a novel, seven transmembrane-domain G protein-coupled acetylcholine receptor (AChR); when expressed in Xenopus oocytes treated with acetylcholine, GAR-2 is able to activate a mammalian G protein-activated inwardly rectifying K+ (GIRK1) channel, but not other channels, suggesting that GAR-2 couples to G proteins of the Gi family; pharmacological analyses indicate, however, that GAR-2 exhibits properties distinct from mammalian muscarinic AChRs; gar-2 is expressed from mid-embryogenesis through adulthood with expression seen in ciliated head neurons, ventral cord neurons, and the HSN (hermaphrodite-specific neuron). | Paper_evidence | WBPaper00004388 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 02 Nov 2006 00:00:00 | ||||||||
Automated_description | Enables G protein-coupled acetylcholine receptor activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of cholinergic synaptic transmission; and response to xenobiotic stimulus. Located in axon. Expressed in neurons. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F47D12.1a | |||||||
F47D12.1b | |||||||||
F47D12.1c | |||||||||
F47D12.1d | |||||||||
F47D12.1e | |||||||||
Corresponding_CDS_history | F47D12.1c:wp275 | ||||||||
Corresponding_transcript | F47D12.1a.1 | ||||||||
F47D12.1b.1 | |||||||||
F47D12.1c.1 | |||||||||
F47D12.1d.1 | |||||||||
F47D12.1e.1 | |||||||||
Other_sequence | JI221387.1 | ||||||||
Dviv_isotig26799 | |||||||||
GO251308.1 | |||||||||
JI465005.1 | |||||||||
CBC06005_1 | |||||||||
FK808445.1 | |||||||||
Associated_feature (15) | |||||||||
Experimental_info | RNAi_result (11) | ||||||||
Expr_pattern | Chronogram723 | ||||||||
Expr1114 | |||||||||
Expr8178 | |||||||||
Expr8179 | |||||||||
Expr10067 | |||||||||
Expr1025714 | |||||||||
Expr1030913 | |||||||||
Expr1151485 | |||||||||
Expr2011945 | |||||||||
Expr2030182 | |||||||||
Drives_construct | WBCnstr00004148 | ||||||||
WBCnstr00009595 | |||||||||
WBCnstr00009870 | |||||||||
WBCnstr00010085 | |||||||||
WBCnstr00013162 | |||||||||
WBCnstr00015039 | |||||||||
WBCnstr00036893 | |||||||||
Construct_product | WBCnstr00001343 | ||||||||
WBCnstr00036893 | |||||||||
Microarray_results (49) | |||||||||
Expression_cluster (178) | |||||||||
Interaction (5) | |||||||||
Map_info | Map | III | Position | -1.39824 | Error | 0.002289 | |||
Positive | Positive_clone | F47D12 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 4334 | |||||||
4407 | |||||||||
Pseudo_map_position | |||||||||
Reference (31) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
[140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag. | |||||||||
Method | Gene |