WormBase Tree Display for Gene: WBGene00001651
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| WBGene00001651 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | gon-2 | Person_evidence | WBPerson261 | |||||
| Sequence_name | T01H8.5 | ||||||||
| Molecular_name (16) | |||||||||
| Other_name | CELE_T01H8.5 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | gon-2 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00001651 | |||||
| WormFlux | gene | WBGene00001651 | |||||||
| NDB | locus_tag | CELE_T01H8.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00001651|UniProtKB=Q93971 | |||||||
| family | PTHR13800 | ||||||||
| NCBI | gene | 172646 | |||||||
| RefSeq | protein | NM_001129034.3 | |||||||
| NM_059914.8 | |||||||||
| NM_001129033.3 | |||||||||
| NM_001373178.2 | |||||||||
| NM_001136316.4 | |||||||||
| SwissProt | UniProtAcc | Q93971 | |||||||
| TrEMBL | UniProtAcc | G5EE91 | |||||||
| A5JYU8 | |||||||||
| G5EGP7 | |||||||||
| G5EGJ6 | |||||||||
| UniProt_GCRP | UniProtAcc | Q93971 | |||||||
| OMIM | gene | 603576 | |||||||
| 605692 | |||||||||
| 607009 | |||||||||
| 608961 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gon | ||||||||
| Allele (294) | |||||||||
| Legacy_information | [C.elegansII] q362 :partial maternal effect gonadless (Z1 and Z4 often fail to divide). OA3: q388ts (zygotic sterile at 25C, fertile 15C, upshift gives Gon progeny), dx12, dx13. Cloned : cosmid rescue (T01H8)[EJ] | ||||||||
| [Lambie EJ] q362 is partial maternal-effect gonadless (Z1, Z4 often fail to divide). q388 is ts allele, fertile at 15C, zygotic sterile at 25C, upshift gives Gon progeny. | |||||||||
| Strain | WBStrain00036616 | ||||||||
| WBStrain00007128 | |||||||||
| WBStrain00007130 | |||||||||
| WBStrain00007119 | |||||||||
| WBStrain00007123 | |||||||||
| WBStrain00007124 | |||||||||
| WBStrain00049840 | |||||||||
| WBStrain00049841 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (58) | |||||||||
| Paralog | WBGene00001796 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001795 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00000425 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00004149 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00008731 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00020972 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00021404 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00021408 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | gon-2 encodes a predicted transmembrane cation channel homologous to the long transient receptor potential channel (LTRPC) subfamily of TRP channels including Drosophila DLTRP and mammalian melastatin and LTRPC7; GON-2 regulates the onset and continuation of post-embryonic mitotic cell divisions in the somatic gonad precursor cells perhaps by mediating an increase in intracellular calcium in response to activating signals. | Paper_evidence | WBPaper00004159 | |||||
| WBPaper00004647 | |||||||||
| WBPaper00018419 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable monoatomic cation channel activity. Involved in defecation; gonad development; and mitotic cell cycle. Predicted to be located in plasma membrane. Expressed in gonad and intestine. Human ortholog(s) of this gene implicated in several diseases, including amyotrophic lateral sclerosis-parkinsonism/dementia complex 1; congenital stationary night blindness 1C; and intestinal hypomagnesemia 1. Is an ortholog of human TRPM3 (transient receptor potential cation channel subfamily M member 3) and TRPM7 (transient receptor potential cation channel subfamily M member 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110867 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7146) | ||||
| DOID:0050534 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:7146) | ||||||
| DOID:0111246 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17994) | ||||||
| DOID:0060883 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17995) | ||||||
| DOID:896 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17995) | ||||||
| DOID:83 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17992) | ||||||
| Molecular_info | Corresponding_CDS | T01H8.5a | |||||||
| T01H8.5b | |||||||||
| T01H8.5c | |||||||||
| T01H8.5d | |||||||||
| T01H8.5e | |||||||||
| Corresponding_CDS_history | T01H8.5:wp74 | ||||||||
| Corresponding_transcript | T01H8.5a.1 | ||||||||
| T01H8.5b.1 | |||||||||
| T01H8.5c.1 | |||||||||
| T01H8.5d.1 | |||||||||
| T01H8.5d.2 | |||||||||
| T01H8.5e.1 | |||||||||
| Other_sequence (30) | |||||||||
| Associated_feature (15) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00004102 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00026161 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00052180 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00052181 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00083926 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00083925 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116718 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035042 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00026160 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3712 | ||||||||
| Expr6568 | |||||||||
| Expr10982 | |||||||||
| Expr1027590 | |||||||||
| Expr1030991 | |||||||||
| Expr1155811 | |||||||||
| Expr2012171 | |||||||||
| Expr2030407 | |||||||||
| Drives_construct | WBCnstr00003790 | ||||||||
| WBCnstr00006319 | |||||||||
| WBCnstr00007206 | |||||||||
| WBCnstr00011621 | |||||||||
| WBCnstr00042687 | |||||||||
| Construct_product | WBCnstr00006319 | ||||||||
| WBCnstr00011621 | |||||||||
| WBCnstr00042687 | |||||||||
| WBCnstr00042688 | |||||||||
| Microarray_results (29) | |||||||||
| Expression_cluster (115) | |||||||||
| Interaction (56) | |||||||||
| Map_info | Map | I | Position | 2.95114 | Error | 0.007035 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | dxDf1 | |||||||
| Positive_clone | T01H8 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| Mapping_data | Multi_point | 3674 | |||||||
| 3675 | |||||||||
| 4381 | |||||||||
| Pos_neg_data | 9323 | ||||||||
| Reference (58) | |||||||||
| Remark | sequence from Pinar Kondu.0105 | ||||||||
| T01H8.3 and T01H8.4 removed. email from JAH 0109 | |||||||||
| Method | Gene |
