WormBase Tree Display for Gene: WBGene00001686
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| WBGene00001686 | SMap | S_parent | Sequence | F33H1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | gpd-4 | Person_evidence | WBPerson1051 | |||||
| Sequence_name | F33H1.2 | ||||||||
| Molecular_name | F33H1.2 | ||||||||
| F33H1.2.1 | |||||||||
| CE01568 | |||||||||
| Other_name | CELE_F33H1.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | gpd-4 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | gpd | ||||||||
| Allele (20) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1),ubiquitous, predominant expression in embryo; sequence closest to gpd-1. [Barrios et al. 1989; HH] | ||||||||
| Strain | WBStrain00055463 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (60) | |||||||||
| Paralog | WBGene00001683 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001684 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00001685 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | gpd-4 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-4 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-4 is required for embryonic and larval development; in C. elegans, GPD-4 and GPD-1 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types. | Paper_evidence | WBPaper00000730 | |||||
| WBPaper00001143 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4141) | ||||
| DOID:3319 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4141) | ||||||
| Molecular_info | Corresponding_CDS | F33H1.2 | |||||||
| Corresponding_transcript | F33H1.2.1 | ||||||||
| Other_sequence (88) | |||||||||
| Associated_feature | WBsf644593 | ||||||||
| WBsf1012983 | |||||||||
| WBsf221974 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00018506 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00052969 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00008168 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00008043 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114592 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00046227 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00014257 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115891 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr778 | ||||||||
| Expr4115 | |||||||||
| Expr1012870 | |||||||||
| Expr1031006 | |||||||||
| Expr1150115 | |||||||||
| Expr2012208 | |||||||||
| Expr2030444 | |||||||||
| Drives_construct | WBCnstr00036770 | ||||||||
| Construct_product | WBCnstr00036770 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (201) | |||||||||
| Interaction (126) | |||||||||
| Map_info | Map | II | Position | 2.16682 | Error | 0.004254 | |||
| Positive | Positive_clone | F33H1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| HH#2-3 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
