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WormBase Tree Display for Gene: WBGene00001686

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Name Class

WBGene00001686SMapS_parentSequenceF33H1
IdentityVersion1
NameCGC_namegpd-4Person_evidenceWBPerson1051
Sequence_nameF33H1.2
Molecular_nameF33H1.2
F33H1.2.1
CE01568
Other_nameCELE_F33H1.2Accession_evidenceNDBBX284602
Public_namegpd-4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpd
Allele (20)
Legacy_information[C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1),ubiquitous, predominant expression in embryo; sequence closest to gpd-1. [Barrios et al. 1989; HH]
StrainWBStrain00055463
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (60)
ParalogWBGene00001683Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001684Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001685Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptiongpd-4 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-4 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-4 is required for embryonic and larval development; in C. elegans, GPD-4 and GPD-1 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types.Paper_evidenceWBPaper00000730
WBPaper00001143
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
DOID:3319Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
Molecular_infoCorresponding_CDSF33H1.2
Corresponding_transcriptF33H1.2.1
Other_sequence (88)
Associated_featureWBsf644593
WBsf1012983
WBsf221974
Experimental_infoRNAi_resultWBRNAi00018506Inferred_automaticallyRNAi_primary
WBRNAi00052969Inferred_automaticallyRNAi_primary
WBRNAi00008168Inferred_automaticallyRNAi_primary
WBRNAi00008043Inferred_automaticallyRNAi_primary
WBRNAi00114592Inferred_automaticallyRNAi_primary
WBRNAi00046227Inferred_automaticallyRNAi_primary
WBRNAi00014257Inferred_automaticallyRNAi_primary
WBRNAi00115891Inferred_automaticallyRNAi_primary
Expr_patternExpr778
Expr4115
Expr1012870
Expr1031006
Expr1150115
Expr2012208
Expr2030444
Drives_constructWBCnstr00036770
Construct_productWBCnstr00036770
Microarray_results (21)
Expression_cluster (201)
InteractionWBInteraction000030796
WBInteraction000036343
WBInteraction000038517
WBInteraction000039203
WBInteraction000043053
WBInteraction000043054
WBInteraction000043785
WBInteraction000044293
WBInteraction000044295
WBInteraction000044439
WBInteraction000044489
WBInteraction000047363
WBInteraction000102293
WBInteraction000102354
WBInteraction000102702
WBInteraction000102895
WBInteraction000105213
WBInteraction000105214
WBInteraction000112874
WBInteraction000153964
WBInteraction000155188
WBInteraction000162890
WBInteraction000162960
WBInteraction000167167
WBInteraction000167168
WBInteraction000167169
WBInteraction000167449
WBInteraction000173192
WBInteraction000173193
WBInteraction000173194
WBInteraction000173195
WBInteraction000184592
WBInteraction000185160
WBInteraction000188073
WBInteraction000190241
WBInteraction000193216
WBInteraction000204106
WBInteraction000209516
WBInteraction000211654
WBInteraction000212519
WBInteraction000220591
WBInteraction000231025
WBInteraction000231093
WBInteraction000233095
WBInteraction000240411
WBInteraction000248145
WBInteraction000255689
WBInteraction000255690
WBInteraction000266545
WBInteraction000269029
WBInteraction000279252
WBInteraction000279392
WBInteraction000283444
WBInteraction000288371
WBInteraction000292298
WBInteraction000296824
WBInteraction000303175
WBInteraction000303317
WBInteraction000303514
WBInteraction000312733
WBInteraction000315231
WBInteraction000321233
WBInteraction000325364
WBInteraction000325365
WBInteraction000325366
WBInteraction000325367
WBInteraction000333509
WBInteraction000333726
WBInteraction000339687
WBInteraction000343655
WBInteraction000347645
WBInteraction000351328
WBInteraction000353125
WBInteraction000353960
WBInteraction000354989
WBInteraction000359105
WBInteraction000363114
WBInteraction000367880
WBInteraction000370763
WBInteraction000370875
WBInteraction000371847
WBInteraction000372694
WBInteraction000376350
WBInteraction000376419
WBInteraction000382121
WBInteraction000386727
WBInteraction000401811
WBInteraction000403431
WBInteraction000408108
WBInteraction000409460
WBInteraction000418371
WBInteraction000418753
WBInteraction000421045
WBInteraction000433254
WBInteraction000437730
WBInteraction000438973
WBInteraction000441005
WBInteraction000442360
WBInteraction000442605
WBInteraction000445721
WBInteraction000449717
WBInteraction000454855
WBInteraction000459181
WBInteraction000461066
WBInteraction000461288
WBInteraction000463879
WBInteraction000463892
WBInteraction000464700
WBInteraction000465308
WBInteraction000465448
WBInteraction000465540
WBInteraction000465803
WBInteraction000466962
WBInteraction000467145
WBInteraction000468685
WBInteraction000469185
WBInteraction000472165
WBInteraction000474121
WBInteraction000536451
WBInteraction000551646
WBInteraction000561404
WBInteraction000563333
WBInteraction000563909
WBInteraction000577576
WBInteraction000579363
WBInteraction000580021
Map_info (3)
Reference (21)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene