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WormBase Tree Display for Gene: WBGene00001686

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Name Class

WBGene00001686SMapS_parentSequenceF33H1
IdentityVersion1
Name (5)
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpd
Allele (20)
Legacy_information[C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1),ubiquitous, predominant expression in embryo; sequence closest to gpd-1. [Barrios et al. 1989; HH]
StrainWBStrain00055463
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (60)
ParalogWBGene00001683Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001684Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001685Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptiongpd-4 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-4 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-4 is required for embryonic and larval development; in C. elegans, GPD-4 and GPD-1 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types.Paper_evidenceWBPaper00000730
WBPaper00001143
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
DOID:3319Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
Molecular_infoCorresponding_CDSF33H1.2
Corresponding_transcriptF33H1.2.1
Other_sequenceES740430.1
AI058165.1
AI374026.1
GE639189.1
HCC10488_1
AA618963.1
FG580977.1
FC813060.1
GR11551
SR05254
AA736325.1
BI772824.1
HGC02473_1
EX540507.1
BE669114.1
Y09455.1
EX555287.1
BE132599.1
FG582761.1
EX537835.1
AI124452.1
FG352581.1
SSC06135_1
FC817962.1
HBC24189_1
CJC00101_1
FG584159.1
AA625023.1
ASC00309_1
HC08782
FC817712.1
BG809060.1
HG07540
HG05254
GP00717
BE491840.1
BG310464.1
AI366650.1
HGC02731_1
HGC01521_1
BI772823.1
SRC06846_1
GO240098.1
CJC15853_1
XI05118
BI772852.1
CR03776
GRC02013_1
FC812102.1
AA917273.1
CRC05840_1
AA635208.1
HC08843
BMC08491_1
BI772873.1
AI111330.1
SSC06131_2
CBC00993_2
HCC11369_1
JI238710.1
EX558805.1
FG582673.1
BE636473.1
AA618739.1
HC08672
BI772827.1
HCC11229_1
FG583585.1
CJC09762_1
AA701696.1
AA736370.1
EX558696.1
CRC01713_1
BI772839.1
CRC02507_1
CR02551
FC818778.1
ES409288.1
CR02591
CD455924.1
BI773192.1
HC06503
CN007695.1
FG583903.1
AA917127.1
HCC11209_1
FG354498.1
EX551653.1
Associated_featureWBsf644593
WBsf1012983
WBsf221974
Experimental_infoRNAi_resultWBRNAi00018506Inferred_automaticallyRNAi_primary
WBRNAi00052969Inferred_automaticallyRNAi_primary
WBRNAi00008168Inferred_automaticallyRNAi_primary
WBRNAi00008043Inferred_automaticallyRNAi_primary
WBRNAi00114592Inferred_automaticallyRNAi_primary
WBRNAi00046227Inferred_automaticallyRNAi_primary
WBRNAi00014257Inferred_automaticallyRNAi_primary
WBRNAi00115891Inferred_automaticallyRNAi_primary
Expr_patternExpr778
Expr4115
Expr1012870
Expr1031006
Expr1150115
Expr2012208
Expr2030444
Drives_constructWBCnstr00036770
Construct_productWBCnstr00036770
Microarray_results (21)
Expression_cluster (201)
Interaction (126)
Map_infoMapIIPosition2.16682Error0.004254
PositivePositive_cloneF33H1Inferred_automaticallyFrom sequence, transcript, pseudogene data
HH#2-3
Pseudo_map_position
Reference (21)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene