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WormBase Tree Display for Gene: WBGene00001954

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Name Class

WBGene00001954EvidenceCGC_data_submission
SMapS_parentSequenceZK682
IdentityVersion3
NameCGC_namehlh-10Person_evidenceWBPerson346
Sequence_nameZK682.4
Molecular_nameZK682.4
ZK682.4.1
CE47615
Other_nameCeABF-1
CELE_ZK682.4Accession_evidenceNDBBX284605
Public_namehlh-10
DB_infoDatabaseAceViewgene5J758
WormQTLgeneWBGene00001954
WormFluxgeneWBGene00001954
NDBlocus_tagCELE_ZK682.4
PanthergeneCAEEL|WormBase=WBGene00001954|UniProtKB=Q23579
familyPTHR23349
NCBIgene191402
RefSeqproteinNM_073000.4
SwissProtUniProtAccQ23579
UniProt_GCRPUniProtAccQ23579
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:26WBPerson1971EventImportedInitial conversion from geneace
311 Mar 2021 09:37:10WBPerson1983Name_changeOther_nameCeABF-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classhlh
Allele (27)
StrainWBStrain00002261
WBStrain00031463
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (32)
ParalogWBGene00001953Caenorhabditis elegansFrom_analysisPanther
WBGene00001962Caenorhabditis elegansFrom_analysisPanther
WBGene00001957Caenorhabditis elegansFrom_analysisPanther
WBGene00001981Caenorhabditis elegansFrom_analysisPanther
WBGene00001956Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionAutomated_descriptionEnables protein heterodimerization activity and transcription corepressor activity. Involved in negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Expressed in ADLL; ADLR; ASEL; ASER; and neurons. Human ortholog(s) of this gene implicated in coronary artery disease and ventricular septal defect. Is an ortholog of human MSC (musculin) and TCF21 (transcription factor 21).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1657Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11632)
DOID:3393Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11632)
Molecular_infoCorresponding_CDSZK682.4
Corresponding_CDS_historyZK682.4:wp231
Corresponding_transcriptZK682.4.1
Other_sequenceCJC01351_1
Associated_featureWBsf652900
WBsf652901
WBsf978808
WBsf1000852
WBsf1000853
WBsf1000854
WBsf1020148
Transcription_factorWBTranscriptionFactor000067
WBTranscriptionFactor000077
Experimental_infoRNAi_resultWBRNAi00038417Inferred_automaticallyRNAi_primary
WBRNAi00059660Inferred_automaticallyRNAi_primary
WBRNAi00022129Inferred_automaticallyRNAi_primary
Expr_patternChronogram385
Expr1673
Expr2960
Expr7899
Expr14595
Expr1011155
Expr1163072
Expr2012490
Expr2030729
Drives_constructWBCnstr00004463
WBCnstr00011045
WBCnstr00012976
WBCnstr00036564
WBCnstr00041175
Construct_productWBCnstr00016001
WBCnstr00036564
Microarray_results (17)
Expression_cluster (56)
Interaction (25)
Map_infoMapVPosition1.974Error0.002284
PositivePositive_cloneZK682Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4405
5401
5405
Pseudo_map_position
ReferenceWBPaper00010373
WBPaper00010818
WBPaper00013489
WBPaper00027309
WBPaper00030829
WBPaper00034761
WBPaper00038491
WBPaper00049921
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene